Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 6:13 p.m.

The MLB's Tuesday schedule includes the Cleveland Guardians taking on the Minnesota Twins.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Twins Game Info

• Cleveland Guardians (87-64) vs. Minnesota Twins (79-71)
• Date: Tuesday, September 17, 2024
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: BSGL

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-136) | MIN: (+116)
• Spread: CLE: -1.5 (+155) | MIN: +1.5 (-188)
• Total: 8 -- Over: (-114) | Under: (-106)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Gavin Williams (Guardians) - 3-9, 5.23 ERA vs Zebby Matthews (Twins) - 1-3, 7.11 ERA

The Guardians will give the ball to Gavin Williams (3-9, 5.23 ERA), who is eyeing win No. 4 on the season, and the Twins will turn to Zebby Matthews (1-3, 7.11 ERA). Williams' team is 3-10-0 against the spread in his starts this season. When Williams starts a game and his team is the favorite on the moneyline, they have a record of 2-7. The Twins have gone 2-4-0 ATS in Matthews' six starts that had a set spread. The Twins were named the moneyline underdog for two Matthews starts this season -- they lost both.

Guardians vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (51.1%)

Guardians vs Twins Moneyline

• Cleveland is a -136 favorite on the moneyline, while Minnesota is a +116 underdog on the road.

Guardians vs Twins Spread

• The Guardians are hosting the Twins and are favored by 1.5 runs (+155 to cover) on the runline. Minnesota is -188 to cover.

Guardians vs Twins Over/Under

• The Guardians-Twins contest on Sept. 17 has been given an over/under of 8 runs. The over is set at -114 and the under at -106.

Bet on Cleveland Guardians vs. Minnesota Twins on FanDuel today!

Guardians vs Twins Betting Trends

• The Guardians have won in 59, or 66.3%, of the 89 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win 29 times in 48 chances when named as a favorite of at least -136 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 68 of their 149 opportunities.
• In 149 games with a line this season, the Guardians have a mark of 79-70-0 against the spread.
• The Twins have won 38.1% of the games this season they were the underdog on the moneyline (16-26).
• When playing as a moneyline underdog with odds of +116 or longer, Minnesota has a 5-11 record (winning only 31.2% of its games).
• The Twins have played in 146 games with an over/under set, and have combined with opponents to go over the total 73 times (73-67-6).
• The Twins have put together a 64-82-0 record against the spread this season (covering 43.8% of the time).

Guardians Player Leaders

• Jose Ramirez leads Cleveland in slugging percentage (.515) and total hits (159) this season. He's batting .273 with an on-base percentage of .331.
• Among all qualifying hitters, he ranks 33rd in batting average, his on-base percentage ranks 51st, and he is 13th in slugging.
• Ramirez will look for his 10th straight game with a hit in this contest. In his last 10 outings he is batting .275 with three doubles, a home run, four walks and an RBI.
• Josh Naylor is batting .245 with 26 doubles, 29 home runs and 55 walks. He's slugging .459 with an on-base percentage of .323.
• Among all qualified, he ranks 88th in batting average, 72nd in on-base percentage and 39th in slugging percentage.
• Naylor has picked up a hit in three games in a row. During his last five outings he is batting .278 with a double, two walks and two RBI.
• Steven Kwan has 138 hits this season and a team-best OBP of .364.
• Kwan has recorded at least one base hit in four straight games. In his last five games he is batting .313 with seven walks.
• Andres Gimenez has eight home runs, 60 RBI and a batting average of .251 this season.

Twins Player Leaders

• Carlos Santana has racked up 116 hits, a team-best for the Twins. He's batting .243 and slugging .433 with an on-base percentage of .330.
• Including all the qualifying hitters in the big leagues, he ranks 95th in batting average, 55th in on-base percentage and 63rd in slugging percentage.
• Santana hopes to build on a six-game hitting streak in this matchup. In his last 10 games he is hitting .306 with a double, three home runs, four walks and seven RBI.
• Willi Castro has a .333 OBP while slugging .387. Both are team-highs. He has a batting average of .249.
• His batting average is 78th among all qualified players, his on-base percentage is 48th, and he is 108th in slugging.
• Ryan Jeffers has 22 doubles, 20 home runs and 31 walks while batting .230.
• Jose Miranda has 28 doubles, four triples, nine home runs and 18 walks while hitting .292.

Guardians vs Twins Head to Head

• 9/16/2024: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2024: 5-3 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 6-3 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/9/2024: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/19/2024: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/18/2024: 11-4 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/17/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/6/2024: 3-1 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 4/4/2024: 4-2 CLE (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 9/6/2023: 2-1 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)

New to FanDuel Sportsbook? You’ll receive $200 in Bonus Bets guaranteed after your first bet of $5+ is placed! See here for full terms and conditions. Learn about today’s other offers at FanDuel Sportsbook Promos.