Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 3

Odds updated as of 12:13 a.m.

The Cleveland Guardians are among the MLB squads in action on Sunday, versus the Minnesota Twins.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Twins Game Info

• Cleveland Guardians (56-54) vs. Minnesota Twins (51-59)
• Date: Sunday, August 3, 2025
• Time: 1:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and MNNT

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-166) | MIN: (+140)
• Spread: CLE: -1.5 (+118) | MIN: +1.5 (-142)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Joey Cantillo (Guardians) - 2-1, 4.14 ERA vs Jose Urena (Twins) - 0-0, 5.40 ERA

The Guardians will call on Joey Cantillo (2-1) versus the Twins and Jose Urena. Cantillo and his team have a record of 3-2-0 against the spread when he starts. Cantillo's team is 2-0 this season when he starts and they're favored on the moneyline. Urena has started two games with set spreads, and the Twins went 1-1-0. The Twins were the moneyline underdog for one Urena start this season -- they won.

Guardians vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (53.3%)

Guardians vs Twins Moneyline

• Minnesota is the underdog, +140 on the moneyline, while Cleveland is a -166 favorite at home.

Guardians vs Twins Spread

• The Guardians are favored by 1.5 runs at home against the Twins. The Guardians are +118 to cover the spread, while the Twins are -142.

Guardians vs Twins Over/Under

• The over/under for the Guardians versus Twins contest on Aug. 3 has been set at 8.5, with -100 odds on the over and -122 odds on the under.

Bet on Cleveland Guardians vs. Minnesota Twins on FanDuel today!

Guardians vs Twins Betting Trends

• The Guardians have won in 29, or 65.9%, of the 44 contests they have been named as odds-on favorites in this year.
• Cleveland has not lost in seven games this year when favored by -166 or better on the moneyline.
• The Guardians' games have gone over the total in 48 of their 107 opportunities.
• The Guardians have posted a record of 55-52-0 against the spread this season.
• The Twins have won 37.1% of the games this season they were the moneyline underdog (13-22).
• In games it has played as a moneyline underdog with odds of +140 or longer, Minnesota has gone 2-4 (33.3%).
• The Twins have had an over/under set by bookmakers 106 times, and have combined with opponents to go over the total in 44 of those games (44-56-6).
• The Twins have covered 50% of their games this season, going 53-53-0 against the spread.

Guardians Player Leaders

• Jose Ramirez leads Cleveland in OBP (.375), slugging percentage (.526) and total hits (121) this season. He has a .300 batting average.
• Among qualified hitters in the majors, his batting average ranks ninth, his on-base percentage ranks 12th, and he is 12th in slugging.
• Ramirez will look for his fifth straight game with a hit in this contest. In his last five games he is hitting .350 with a double, a home run, three walks and three RBIs.
• Steven Kwan has 20 doubles, a triple, nine home runs and 40 walks. He's batting .285 and slugging .404 with an on-base percentage of .348.
• Among all qualifying hitters, he ranks 22nd in batting average, 47th in on-base percentage and 102nd in slugging percentage.
• Carlos Santana is batting .230 with a .343 slugging percentage and 46 RBI this year.
• Santana has recorded a hit in five straight games. During his last five outings he is batting .350 with a double, a walk and two RBIs.
• Kyle Manzardo is batting .237 with a .311 OBP and 48 RBI for Cleveland this season.

Twins Player Leaders

• Trevor Larnach has 15 doubles, a triple, 13 home runs and 37 walks while hitting .244. He's slugging .400 with an on-base percentage of .317.
• Including all qualified hitters in the majors, his batting average places him 115th, his on-base percentage is 104th, and he is 109th in slugging.
• Ryan Jeffers has 19 doubles, seven home runs and 34 walks while batting .255. He's slugging .393 with an on-base percentage of .343.
• Brooks Lee has 10 doubles, 10 home runs and 16 walks while batting .250.
• Kody Clemens is batting .215 with seven doubles, three triples, 12 home runs and 18 walks.

Guardians vs Twins Head to Head

• 8/2/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/1/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/21/2025: 5-1 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/1/2025: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/30/2025: 4-2 CLE (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2025: 11-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/17/2024: 4-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2024: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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