Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for May 9

Odds updated as of 2:11 a.m.

On Saturday in MLB, the Cleveland Guardians are playing the Minnesota Twins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Guardians vs Twins Game Info

• Cleveland Guardians (21-19) vs. Minnesota Twins (16-23)
• Date: Saturday, May 9, 2026
• Time: 6:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and Twins.TV

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-112) | MIN: (-104)
• Spread: CLE: +1.5 (-184) | MIN: -1.5 (+152)
• Total: 7.5 -- Over: (-122) | Under: (+100)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 0-5, 4.58 ERA vs Joe Ryan (Twins) - 2-3, 3.72 ERA

The Guardians will look to Tanner Bibee (0-5) versus the Twins and Joe Ryan (2-3). When Bibee starts, his team is 1-7-0 against the spread this season. Bibee and his team have lost each of the four games he's started as the moneyline favorite. The Twins have gone 4-4-0 ATS in Ryan's eight starts that had a set spread. The Twins have a 1-3 record in Ryan's four starts this season when they were the moneyline underdog.

Guardians vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (54.8%)

Guardians vs Twins Moneyline

• Looking at the moneyline for Twins-Guardians, Minnesota is the underdog at -104, and Cleveland is -112 playing at home.

Guardians vs Twins Spread

• The Twins are 1.5-run favorites against the spread for this matchup with the Guardians. The Twins are +152 to cover, while the Guardians are -184 to cover as a 1.5-run underdog on the runline.

Guardians vs Twins Over/Under

• The over/under for Guardians-Twins on May 9 is 7.5. The over is -122, and the under is +100.

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Guardians vs Twins Betting Trends

• The Guardians have been favorites in 18 games this season and have come away with the win nine times (50%) in those contests.
• This season Cleveland has been victorious nine times in 18 chances when named as a favorite of at least -112 on the moneyline.
• Contests with the Guardians have gone over the total set by oddsmakers in 20 of 39 chances this season.
• In 39 games with a line this season, the Guardians have a mark of 21-18-0 against the spread.
• The Twins have gone 12-16 in games they were the underdog on the moneyline (winning 42.9% of those games).
• Minnesota is 12-14 (winning 46.2% of its games) when it has played as a moneyline underdog of -104 or longer.
• The Twins have had an over/under set by bookmakers 39 times, and have combined with opponents to go over the total in 25 of those games (25-13-1).
• The Twins have put together an 18-21-0 record ATS this season (covering 46.2% of the time).

Guardians Player Leaders

• Jose Ramirez is batting .219 with eight doubles, six home runs and 28 walks. He has an on-base percentage of .345 while slugging .397.
• Among qualified hitters, he ranks 138th in batting average, his on-base percentage ranks 71st, and he is 92nd in slugging.
• Ramirez hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .235 with four walks and an RBI.
• Chase DeLauter leads Cleveland in OBP (.392), slugging percentage (.548) and total hits (38) this season. He's batting .306.
• He ranks 18th in batting average, 18th in on-base percentage and 15th in slugging in MLB.
• DeLauter heads into this game looking to extend his 11-game hit streak. During his last 10 games he is hitting .514 with five doubles, a home run, five walks and seven RBIs.
• Brayan Rocchio has collected 33 base hits, an OBP of .348 and a slugging percentage of .368 this season.
• Rocchio has picked up a hit in two straight games. During his last five outings he is hitting .176 with two walks.
• Steven Kwan is batting .221 with a .321 OBP and nine RBI for Cleveland this season.
• Kwan has hit safely in two games in a row. During his last five outings he is batting .158 with a double and three walks.

Twins Player Leaders

• Byron Buxton has a slugging percentage of .542 and has 39 hits, both team-best numbers for the Twins. He's batting .255 and with an on-base percentage of .307.
• Including all qualifying players in the majors, he is 81st in batting average, 125th in on-base percentage and 17th in slugging percentage.
• Ryan Jeffers' .408 on-base percentage paces his team. He has a batting average of .300 while slugging .520.
• Including all qualified hitters, he ranks 25th in batting average, ninth in on-base percentage and 26th in slugging percentage.
• Brooks Lee has five doubles, five home runs and nine walks while hitting .278.
• Luke Keaschall has eight doubles, a home run and 16 walks while batting .236.

Guardians vs Twins Head to Head

• 5/8/2026: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/21/2025: 6-2 MIN (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/20/2025: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/20/2025: 6-0 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/3/2025: 5-4 MIN (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/2/2025: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/1/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/21/2025: 5-1 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/1/2025: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)

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