Guardians vs Rangers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 5:13 a.m.

In MLB action on Saturday, the Cleveland Guardians play the Texas Rangers.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Rangers Game Info

• Cleveland Guardians (86-74) vs. Texas Rangers (81-79)
• Date: Saturday, September 27, 2025
• Time: 7:15 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: FOX

Guardians vs Rangers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-156) | TEX: (+132)
• Spread: CLE: -1.5 (+142) | TEX: +1.5 (-172)
• Total: 7 -- Over: (-120) | Under: (-102)

Guardians vs Rangers Probable Starting Pitchers

Probable Pitchers: Joey Cantillo (Guardians) - 5-3, 3.21 ERA vs Jake Latz (Rangers) - 2-0, 2.80 ERA

This contest's pitching matchup is set, as the Guardians will send Joey Cantillo (5-3) to the mound, while Jake Latz (2-0) will get the nod for the Rangers. Cantillo and his team have a record of 7-5-0 against the spread when he starts. Cantillo's team has won 57.1% of his starts when they are favored on the moneyline (4-3). The Rangers have a 4-2-0 record against the spread in Latz's starts. The Rangers are 2-3 in Latz's five starts this season that they were the moneyline underdog.

Guardians vs Rangers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rangers win (57.7%)

Guardians vs Rangers Moneyline

• The moneyline numbers for Guardians vs. Rangers reveal Cleveland as the favorite (-156) and Texas as the underdog (+132) on the road.

Guardians vs Rangers Spread

• The Guardians are hosting the Rangers and are favored by 1.5 runs (+142 to cover) on the runline. Texas is -172 to cover.

Guardians vs Rangers Over/Under

• A combined run total of 7 has been set for Guardians-Rangers on Sept. 27, with the over at -120 and the under at -102.

Bet on Cleveland Guardians vs. Texas Rangers on FanDuel today!

Guardians vs Rangers Betting Trends

• The Guardians have come away with 42 wins in the 67 contests they have been listed as the favorites in this season.
• Cleveland has a record of 10-3 when favored by -156 or more this year.
• The Guardians and their opponents have hit the over in 67 of their 156 games with a total set by oddsmakers this season.
• The Guardians are 85-71-0 against the spread in their 156 games with a line set by sportsbooks this season.
• The Rangers have gone 31-46 in games they were listed as the moneyline underdog (winning 40.3% of those games).
• When playing as a moneyline underdog with odds of +132 or longer, Texas has a 3-9 record (winning just 25% of its games).
• The Rangers have had an over/under set by bookmakers 159 times, and have combined with opponents to go over the total in 70 of those games (70-87-2).
• The Rangers have covered 52.8% of their games this season, going 84-75-0 against the spread.

Guardians Player Leaders

• Jose Ramirez has 165 hits and an OBP of .360, both of which are tops among Cleveland hitters this season. He has a .283 batting average and a slugging percentage of .505.
• He is 21st in batting average, 20th in on-base percentage, and 15th in slugging among qualified hitters in baseball.
• Steven Kwan has an OPS of .709, fueled by an OBP of .332 and a team-best slugging percentage of .378 this season. He's batting .274.
• He ranks 33rd in batting average, 72nd in on-base percentage and 126th in slugging in MLB.
• Kyle Manzardo is batting .232 with a .454 slugging percentage and 70 RBI this year.
• Angel Martinez is batting .226 with a .268 OBP and 45 RBI for Cleveland this season.

Rangers Player Leaders

• Adolis Garcia has 28 doubles, 18 home runs and 27 walks while hitting .226. He's slugging .391 with an on-base percentage of .270.
• Including all the qualifying hitters in MLB, he ranks 142nd in batting average, 147th in on-base percentage and 115th in slugging percentage.
• Josh Jung is hitting .249 with 21 doubles, a triple, 14 home runs and 26 walks. He's slugging .386 with an on-base percentage of .291.
• Including all qualified players, he is 95th in batting average, 134th in on-base percentage and 119th in slugging percentage.
• Jake Burger has 15 doubles, a triple, 16 home runs and 12 walks while hitting .236.
• Jonah Heim has 14 doubles, 11 home runs and 32 walks while batting .215.

Guardians vs Rangers Head to Head

• 9/26/2025: 7-3 TEX (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/24/2025: 5-0 TEX (Favorite: Rangers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/23/2025: 10-0 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/22/2025: 4-3 TEX (Favorite: Rangers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/25/2024: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/24/2024: 13-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/23/2024: 5-3 TEX (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/15/2024: 4-0 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 5/14/2024: 7-4 CLE (Favorite: Rangers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/13/2024: 7-0 CLE (Favorite: Rangers, Spread: -1.5, Total: 9, Favorite Moneyline: -108, Underdog Moneyline: -108)

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