Guardians vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 24

Odds updated as of 4:11 a.m.

Monday's slate in the MLB includes a matchup between the Cleveland Guardians and the Los Angeles Angels.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Angels Game Info

• Cleveland Guardians (65-66) vs. Los Angeles Angels (52-79)
• Date: Monday, August 24, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV, KCOP 13, and CleGuardians.TV

Guardians vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-164) | LAA: (+138)
• Spread: CLE: -1.5 (+100) | LAA: +1.5 (-120)
• Total: 8 -- Over: (-114) | Under: (-106)

Guardians vs Angels Probable Starting Pitchers

Probable Pitchers: Parker Messick (Guardians) - 9-8, 2.54 ERA vs George Klassen (Angels) - 2-1, 3.74 ERA

The Guardians will give the nod to Parker Messick (9-8, 2.54 ERA), who is eyeing win No. 10 on the season, and the Angels will turn to George Klassen (2-1, 3.74 ERA). Messick and his team are 12-13-0 ATS this season when he starts. Messick's team has been victorious in 42.1% of the games he's started as the moneyline favorite with a record of 8-11. The Angels have a 4-1-0 record against the spread in Klassen's starts. The Angels have a 4-1 record in Klassen's five starts this season when they were the underdog on the moneyline.

Guardians vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52.9%)

Guardians vs Angels Moneyline

• The moneyline numbers for Guardians vs. Angels reveal Cleveland as the favorite (-164) and Los Angeles as the underdog (+138) despite being the home team.

Guardians vs Angels Spread

• The Angels are +1.5 on the run line against the Guardians. The Angels are -120 to cover, and the Guardians are +100.

Guardians vs Angels Over/Under

• A total of 8 runs has been set for the Guardians-Angels contest on Aug. 24, with the over available at -114 and the under at -106.

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Guardians vs Angels Betting Trends

• The Guardians have come away with 36 wins in the 73 contests they have been listed as the favorites in this season.
• This year Cleveland has won five of eight games when listed as at least -164 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 60 of their 125 opportunities.
• The Guardians have an against the spread mark of 60-65-0 in 125 games with a line this season.
• The Angels are 38-65 in games they were the underdog on the moneyline (winning 36.9% of those games).
• When it has played as a moneyline underdog with odds of +138 or longer, Los Angeles has a record of 14-20 (41.2%).
• The Angels have played in 130 games with an over/under set, and have combined with their opponents to go over the total 52 times (52-75-3).
• The Angels have put together a 68-62-0 record against the spread this season.

Guardians Player Leaders

• Chase DeLauter has 119 hits to go with a slugging percentage of .450, both of which are best among Cleveland hitters this season. He has a .288 batting average and an on-base percentage of .363.
• Among qualifying hitters, he is 16th in batting average, his on-base percentage ranks 25th, and he is 46th in slugging.
• Jose Ramirez is batting .235 with 20 doubles, 10 home runs and 54 walks. He's slugging .375 with an on-base percentage of .335.
• Among qualifiers, he ranks 109th in batting average, 66th in on-base percentage and 115th in slugging percentage.
• Steven Kwan leads Cleveland with an OBP of .370 this season while batting .264 with 69 walks and 61 runs scored.
• Brayan Rocchio has been key for Cleveland with 109 hits, an OBP of .311 plus a slugging percentage of .368.

Angels Player Leaders

• Mike Trout a has .380 on-base percentage to lead the Angels. He's batting .239 while slugging .433.
• Including all the qualifying players in the big leagues, his batting average places him 104th, his on-base percentage is 10th, and he is 63rd in slugging.
• Zach Neto has racked up 120 hits while slugging .436. Both lead his team. He has a batting average of .237 with an on-base percentage of .317.
• Including all qualifying players, his batting average puts him 107th, his on-base percentage ranks 94th, and he is 60th in slugging.
• Vaughn Grissom has 18 doubles, seven home runs and 23 walks while batting .248.
• Moises Ballesteros is batting .213 with nine doubles, six home runs and 22 walks.

Guardians vs Angels Head to Head

• 5/13/2026: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/12/2026: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/11/2026: 7-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/1/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 5/31/2025: 7-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/30/2025: 4-1 LAA (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/6/2025: 6-2 LAA (Favorite: Guardians, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/5/2025: 10-4 LAA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/4/2025: 8-6 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/26/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

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