Golden Knights vs Ducks NHL Prediction, Odds, Picks, Best Bets for Nov. 22

The Saturday schedule in the NHL includes a matchup between the Vegas Golden Knights and the Anaheim Ducks.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital info about today's NHL betting odds.

Golden Knights vs Ducks Game Info

• Vegas Golden Knights (10-4-6) vs. Anaheim Ducks (13-7-1)
• Date: Saturday, November 22, 2025
• Time: 10 p.m. ET
• Venue: Honda Center -- Anaheim, California
• Coverage: ESPN+

Golden Knights vs Ducks Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Golden Knights vs Ducks Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Golden Knights win (64.2%)

Golden Knights vs Ducks Puck Line

• The Ducks are underdogs by 1.5 goals. The Ducks are -215 to cover the spread, and the Golden Knights are +172.

Golden Knights vs Ducks Over/Under

• The Golden Knights-Ducks matchup on Nov. 22 has been given an over/under of 6.5 goals. The over is +100 and the under is -122.

Golden Knights vs Ducks Moneyline

• Anaheim is the underdog, +118 on the moneyline, while Vegas is a -142 favorite despite being on the road.

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