Giants vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 27

Odds updated as of 5:13 a.m.

On Saturday in MLB, the San Francisco Giants are up against the Colorado Rockies.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs Rockies Game Info

• San Francisco Giants (79-81) vs. Colorado Rockies (43-117)
• Date: Saturday, September 27, 2025
• Time: 4:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and COLR

Giants vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-240) | COL: (+198)
• Spread: SF: -1.5 (-110) | COL: +1.5 (-110)
• Total: 8 -- Over: (-108) | Under: (-112)

Giants vs Rockies Probable Starting Pitchers

Probable Pitchers: Justin Verlander (Giants) - 3-11, 3.88 ERA vs Kyle Freeland (Rockies) - 5-16, 5.00 ERA

The Giants will give the nod to Justin Verlander (3-11, 3.88 ERA), who is eyeing win No. 4 on the season, and the Rockies will counter with Kyle Freeland (5-16, 5.00 ERA). Verlander and his team have a record of 9-19-0 against the spread when he starts. Verlander's team is 4-11 this season when he starts and they are the moneyline favorite. The Rockies are 13-16-0 ATS in Freeland's 29 starts with a set spread. The Rockies have a 7-20 record in Freeland's 27 starts this season when they were the moneyline underdog.

Giants vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (64.4%)

Giants vs Rockies Moneyline

• Looking at the moneyline for Giants-Rockies, San Francisco is the favorite at -240, and Colorado is +198 playing on the road.

Giants vs Rockies Spread

• The Rockies are +1.5 on the run line against the Giants. The Rockies are -110 to cover, and the Giants are -110.

Giants vs Rockies Over/Under

• A total of 8 runs has been set for the Giants-Rockies game on Sept. 27, with the over available at -108 and the under at -112.

Bet on San Francisco Giants vs. Colorado Rockies on FanDuel today!

Giants vs Rockies Betting Trends

• The Giants have been favorites in 92 games this season and have come away with the win 48 times (52.2%) in those contests.
• This season San Francisco has been victorious four times in five chances when named as a favorite of at least -240 on the moneyline.
• The Giants and their opponents have gone over in 77 of their 159 games with a total set by sportsbooks this season.
• The Giants are 75-84-0 against the spread in their 159 games that had a posted line this season.
• The Rockies have won 38 of the 150 games they were the underdog on the moneyline this season (25.3%).
• Colorado has a 13-55 record (winning only 19.1% of its games) when it has played as a moneyline underdog of +198 or longer.
• In the 155 games bookmakers have set an over/under for the Rockies, they have combined with opponents to go over the total 69 times (69-81-5).
• The Rockies have covered 40% of their games this season, going 62-93-0 against the spread.

Giants Player Leaders

• Rafael Devers leads San Francisco with 151 hits and an OBP of .373 this season. He has a .252 batting average and a slugging percentage of .476.
• Among the qualified hitters in MLB, his batting average ranks 90th, his on-base percentage ranks ninth, and he is 33rd in slugging.
• Devers will look for his seventh straight game with a hit in this contest. During his last 10 games he is hitting .211 with a double, three home runs, eight walks and five RBIs.
• Willy Adames is batting .226 with 22 doubles, two triples, 29 home runs and 80 walks, while slugging .420 with an on-base percentage of .320.
• Among all qualified hitters, he is 142nd in batting average, 95th in on-base percentage and 82nd in slugging percentage.
• Adames takes a three-game streak with at least one hit into this matchup. During his last five outings he is batting .200 with a double, a home run, two walks and four RBIs.
• Jung Hoo Lee has 146 hits this season and has a slash line of .264/.326/.407.
• Lee enters this game with three games in a row with at least one hit. During his last five outings he is hitting .350 with a double, a triple and an RBI.
• Heliot Ramos leads San Francisco in slugging percentage (.403) thanks to 46 extra-base hits.
• Ramos has hit safely in four straight games. During his last five outings he is batting .250 with three home runs and seven RBIs.

Rockies Player Leaders

• Hunter Goodman has put up a team-high OBP (.320) and slugging percentage (.514), and leads the Rockies in hits (147, while batting .276).
• Including all the qualified hitters in MLB, he is 29th in batting average, 95th in on-base percentage and 13th in slugging percentage.
• Mickey Moniak is batting .270 with 20 doubles, eight triples, 24 home runs and 22 walks. He's slugging .518 with an on-base percentage of .306.
• Jordan Beck has racked up an on-base percentage of .320, a team-high for the Rockies.
• Tyler Freeman has 20 doubles, two triples, two home runs and 34 walks while hitting .281.

Giants vs Rockies Head to Head

• 9/26/2025: 6-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/3/2025: 10-8 SF (Favorite: Giants, Spread: -1.5, Total: 11.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 9/2/2025: 7-4 SF (Favorite: Giants, Spread: -1.5, Total: 10.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 9/1/2025: 8-2 SF (Favorite: Giants, Spread: -1.5, Total: 11.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/12/2025: 8-7 COL (Favorite: Giants, Spread: -1.5, Total: 11, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 6/11/2025: 10-7 SF (Favorite: Giants, Spread: -1.5, Total: 10.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/10/2025: 6-5 SF (Favorite: Giants, Spread: -1.5, Total: 11, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/4/2025: 9-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -390, Underdog Moneyline: +310)
• 5/3/2025: 6-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 5/2/2025: 4-0 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -290, Underdog Moneyline: +235)

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