Giants vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 13

Odds updated as of 12:11 a.m.

The MLB's Wednesday slate includes the San Francisco Giants taking on the San Diego Padres.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Giants vs Padres Game Info

• San Francisco Giants (59-60) vs. San Diego Padres (67-52)
• Date: Wednesday, August 13, 2025
• Time: 3:45 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and SDPA

Giants vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-118) | SD: (-100)
• Spread: SF: +1.5 (-215) | SD: -1.5 (+176)
• Total: 7.5 -- Over: (-112) | Under: (-108)

Giants vs Padres Probable Starting Pitchers

Probable Pitchers: Kai-Wei Teng (Giants) - 1-1, 5.40 ERA vs Nick Pivetta (Padres) - 11-4, 2.94 ERA

The Giants will look to Kai-Wei Teng (1-1) against the Padres and Nick Pivetta (11-4). Teng and his team failed to cover the spread in his only opportunity this season as a starter. This will be Teng's first game as the moneyline favorite this season. The Padres are 13-10-0 ATS in Pivetta's 23 starts with a set spread. The Padres have a 5-3 record in Pivetta's eight starts this season when they were the moneyline underdog.

Giants vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (57.3%)

Giants vs Padres Moneyline

• San Francisco is a -118 favorite on the moneyline, while San Diego is a -100 underdog on the road.

Giants vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Giants. The Padres are +176 to cover, while the Giants are -215 to cover as a 1.5-run underdog on the runline.

Giants vs Padres Over/Under

• An over/under of 7.5 has been set for Giants-Padres on Aug. 13, with the over being -112 and the under -108.

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Giants vs Padres Betting Trends

• The Giants have been chosen as favorites in 75 games this year and have walked away with the win 38 times (50.7%) in those games.
• This year San Francisco has won 36 of 69 games when listed as at least -118 on the moneyline.
• The Giants and their opponents have hit the over in 53 of their 119 games with a total set by oddsmakers this season.
• The Giants have posted a record of 50-69-0 against the spread this season.
• The Padres have won 26 of the 52 games they were the underdog on the moneyline this season (50%).
• San Diego has a 24-23 record (winning 51.1% of its games) when playing as a moneyline underdog of -100 or longer.
• The Padres have played in 117 games with an over/under set, and have combined with their opponents to go over the total 50 times (50-64-3).
• The Padres have gone 64-53-0 against the spread this season.

Giants Player Leaders

• Rafael Devers leads San Francisco with 114 hits and an OBP of .381 this season. He has a .256 batting average and a slugging percentage of .472.
• Among qualified hitters in the majors, he ranks 84th in batting average, 11th in on-base percentage, and 40th in slugging.
• Jung Hoo Lee has 27 doubles, nine triples, six home runs and 38 walks. He's batting .256 and slugging .405 with an on-base percentage of .322.
• He is 84th in batting average, 91st in on-base percentage and 101st in slugging in MLB.
• Willy Adames is batting .227 with a .400 slugging percentage and 61 RBI this year.
• Heliot Ramos has an OPS of .758, fueled by an OBP of .346 and a team-best slugging percentage of .412 this season.

Padres Player Leaders

• Manny Machado has put up a slugging percentage of .491 and has 136 hits, both team-high figures for the Padres. He's batting .297 and with an on-base percentage of .359.
• Including all the qualifying hitters in the big leagues, his batting average puts him 10th, his on-base percentage ranks 29th, and he is 24th in slugging.
• Fernando Tatis Jr. is hitting .264 with 21 doubles, two triples, 17 home runs and 66 walks. He's slugging .435 with an on-base percentage of .366.
• He is 66th in batting average, 21st in on-base percentage and 76th in slugging percentage in the majors.
• Luis Arraez is hitting .292 with 23 doubles, four triples, six home runs and 24 walks.
• Xander Bogaerts is hitting .268 with 25 doubles, 10 home runs and 46 walks.

Giants vs Padres Head to Head

• 8/11/2025: 4-1 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/5/2025: 3-2 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/4/2025: 6-5 SF (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/3/2025: 3-2 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 6/2/2025: 1-0 SD (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/30/2025: 5-3 SD (Favorite: Padres, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/29/2025: 7-4 SD (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2024: 4-3 SD (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 9/14/2024: 8-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 9/13/2024: 5-0 SD (Favorite: Padres, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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