Giants vs Mariners Prediction, Odds, Moneyline, Spread & Over/Under for April 6

Odds updated as of 3:12 p.m.

The MLB slate on Sunday includes the San Francisco Giants taking on the Seattle Mariners.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Giants vs Mariners Game Info

• San Francisco Giants (7-1) vs. Seattle Mariners (3-6)
• Date: Sunday, April 6, 2025
• Time: 4:05 p.m. ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: NBCS-BA and ROOT Sports NW

Giants vs Mariners Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-120) | SEA: (+102)
• Spread: SF: +1.5 (-205) | SEA: -1.5 (+168)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Giants vs Mariners Probable Starting Pitchers

Probable Pitchers: Jordan Hicks (Giants) - 1-0, 0.00 ERA vs Bryan Woo (Mariners) - 1-0, 1.50 ERA

The Giants will give the nod to Jordan Hicks (1-0, 0.00 ERA), who is eyeing win No. 2 on the season, and the Mariners will counter with Bryan Woo (1-0, 1.50 ERA). Hicks helped his team cover the spread in his only opportunity this season as a starter. This will be Hicks' first game as the moneyline favorite this season. Woo has started just one game with a set spread, which the Mariners failed to cover. The Mariners have always been the moneyline underdog when Woo starts this season.

Giants vs Mariners Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (55.4%)

Giants vs Mariners Moneyline

• Looking at the moneyline for Mariners-Giants, Seattle is the underdog at +102, and San Francisco is -120 playing at home.

Giants vs Mariners Spread

• The Mariners are 1.5-run favorites against the spread for this matchup with the Giants. The Mariners are +168 to cover, while the Giants are -205 to cover as a 1.5-run underdog on the runline.

Giants vs Mariners Over/Under

• The over/under for Giants-Mariners on April 6 is 7.5. The over is -110, and the under is -110.

Bet on San Francisco Giants vs. Seattle Mariners on FanDuel today!

Giants vs Mariners Betting Trends

• The Giants have been named as the favorite five times this year and have yet to lose any of those games.
• San Francisco has not lost in four games this year when favored by -120 or better on the moneyline.
• Contests with the Giants have gone over the total set by bookmakers in five of eight chances this season.
• In eight games with a line this season, the Giants have a mark of 6-2-0 against the spread.
• The Mariners have gone 1-2 in games they were the underdog on the moneyline (winning 33.3% of those games).
• Seattle has played as a moneyline underdog of +102 or longer in only two games this season, which it split 1-1.
• The Mariners have combined with opponents to hit the over on the total two times this season for a 2-6-1 record against the over/under.
• The Mariners have gone 3-6-0 ATS this season.

Giants Player Leaders

• Wilmer Flores is hitting .250 with four home runs and a walk. He has an on-base percentage of .294 and a slugging percentage of .625.
• Among all qualified hitters in MLB, his batting average ranks 80th, his on-base percentage ranks 117th, and he is 25th in slugging.
• Flores will look for his fourth straight game with a hit in this contest. In his last five games he is batting .286 with two home runs and seven RBI.
• Heliot Ramos has 11 hits to go with a slugging percentage of .657, both of which rank first among San Francisco hitters this season. He's batting .314 with an on-base percentage of .333.
• Among qualified hitters, his batting average ranks him 37th, his on-base percentage 81st, and his slugging percentage 14th.
• Ramos has picked up at least one hit in eight straight games. During his last eight games he is batting .314 with three doubles, three home runs, a walk and eight RBI.
• Matt Chapman has nine hits this season and has a slash line of .310/.429/.586.
• Chapman heads into this game with three games in a row with at least one hit. In his last five games he is hitting .333 with two doubles, a home run, five walks and six RBI.
• Jung Hoo Lee has been key for San Francisco with nine hits, an OBP of .387 plus a slugging percentage of .500.
• Lee heads into this game on a six-game hitting streak. In his last seven games he is batting .321 with five doubles, three walks and three RBI.

Mariners Player Leaders

• Julio Rodriguez has racked up an on-base percentage of .375 and has seven hits, both team-high figures for the Mariners. He's batting .219 and slugging .469.
• Including all the qualified hitters in MLB, his batting average ranks 118th, his on-base percentage is 46th, and he is 69th in slugging.
• Jorge Polanco is batting .450 with two home runs and a walk. He's slugging .750 with an on-base percentage of .476.
• Dylan Moore is hitting .400 with two home runs and three walks.
• Randy Arozarena is hitting .129 with two doubles, two home runs and seven walks.

Giants vs Mariners Head to Head

• 4/5/2025: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 4/4/2025: 10-9 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/25/2024: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/24/2024: 4-3 SF (Favorite: Mariners, Spread: -1.5, Total: 6, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/23/2024: 6-5 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 7/5/2023: 2-0 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 7/4/2023: 6-0 SEA (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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