Florida vs Missouri Prediction, Odds, Picks, Best Bets for Week 5 2026

The Florida Gators are among the college football teams busy on Saturday, versus the Missouri Tigers.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Florida vs Missouri Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Florida: (-215) | Missouri: (+176)
• Spread: Florida: -4.5 (-120) | Missouri: +4.5 (-102)
• Total: 56.5 -- Over: (-115) | Under: (-105)

Florida vs Missouri Betting Trends

• Florida's record against the spread is 3-1-0.
• Florida owns one win ATS (1-1) as a 4.5-point favorite or greater this year.
• This season, three of Florida's four games have hit the over.
• Missouri has one win against the spread this year.
• A pair of Missouri four games in 2026 have hit the over.

Florida vs Missouri Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Gators win (50.4%)

Florida vs Missouri Point Spread

Missouri is an underdog by 4.5 points versus Florida. Missouri is -102 to cover the spread, and Florida is -120.

Florida vs Missouri Over/Under

An over/under of 56.5 has been set for Florida-Missouri on Oct. 3, with the over being -115 and the under -105.

Florida vs Missouri Moneyline

Missouri is the underdog, +176 on the moneyline, while Florida is a -215 favorite.

Florida vs. Missouri Points Insights

Florida vs. Missouri Game Info

• Game day: Saturday, October 3, 2026
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Columbia, Missouri
• Stadium: Memorial Stadium/Faurot Field

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Check out even more in-depth Florida vs. Missouri analysis on FanDuel Research.