Duke vs NC State Prediction, Odds, Picks, Best Bets for Week 10 2026

On Saturday in college football, the Duke Blue Devils are playing the NC State Wolfpack.

We've got you covered, in terms of the most important info regarding NCAA football betting lines, before you make your wager on FanDuel Sportsbook.

Duke vs NC State Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Duke: (-188) | NC State: (+158)
• Spread: Duke: -4.5 (-110) | NC State: +4.5 (-110)
• Total: 51.5 -- Over: (-115) | Under: (-105)

Duke vs NC State Betting Trends

• Duke is 6-2-0 against the spread this season.
• On the season, Duke is 4-1 as 4.5-point or better favorites.
• Out of eight Duke games so far this season, three have gone over the total.
• Against the spread, NC State is 3-5-0 this season.
• NC State is winless ATS (0-1) when playing as at least 4.5-point underdogs this season.
• NC State has played eight games this year, and five of them have hit the over.

Duke vs NC State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Blue Devils win (78.6%)

Duke vs NC State Point Spread

Duke is favored by 4.5 points against NC State. Duke is -110 to cover the spread, while NC State is -110.

Duke vs NC State Over/Under

A total of 51.5 points has been set for the Duke-NC State game on Nov. 7, with the over available at -115 and the under at -105.

Duke vs NC State Moneyline

Duke is a -188 favorite on the moneyline, while NC State is a +158 underdog.

Duke vs. NC State Points Insights

Duke vs. NC State Game Info

• Game day: Saturday, November 7, 2026
• Game time: 12:30 p.m. ET
• TV channel: The CW
• Location: Raleigh, North Carolina
• Stadium: Wayne Day Family Field at Carter-Finley Stadium

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Check out even more in-depth Duke vs. NC State analysis on FanDuel Research.