Duke vs Alabama Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament Elite Eight

The No. 1 seed Duke Blue Devils (34-3) will take on the No. 2 seed Alabama Crimson Tide (28-8) in the NCAA Tournament Elite Eight on Saturday at Prudential Center, airing on TBS beginning at 8:49 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. Alabama Game Info and Odds

• Game day: Saturday, March 29, 2025
• Game time: 8:49 p.m. ET
• TV channel: TBS
• Location: Newark, New Jersey
• Arena: Prudential Center

Duke vs. Alabama Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (68%)

Duke is a 6.5-point favorite against Alabama on Saturday and the over/under is set at 174.5 points. Here are some betting trends and insights before you decide to wager on the outing.

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Duke vs. Alabama: ATS Betting Stats and Trends

• Duke has put together a 24-13-0 ATS record so far this year.
• Alabama has won 21 games against the spread this year, while failing to cover 15 times.
• As a 6.5-point underdog or more in 2024-25, Alabama is 1-0 against the spread compared to the 22-11 ATS record Duke racks up as a 6.5-point favorite.
• The Blue Devils have done a better job covering the spread on the road (9-2-0) than they have in home games (11-6-0).
• In 2024-25 against the spread, the Crimson Tide have a lower winning percentage at home (.533, 8-7-0 record) than on the road (.667, 8-4-0).

Duke vs. Alabama: Moneyline Betting Stats

• Duke has been chosen as the moneyline favorite in 35 games this year and has walked away with the win 32 times (91.4%) in those games.
• The Blue Devils have not lost in 29 games this year when favored by -315 or better on the moneyline.
• Alabama has won five of the eight games it was the moneyline underdog this season (62.5%).
• The Crimson Tide have played as a moneyline underdog of +250 or longer in just one game this season, which they won.
• Oddsmakers have implied with the moneyline set for this matchup that Duke has a 75.9% chance of pulling out a win.

Duke vs. Alabama Head-to-Head Comparison

• Duke is outscoring opponents by 21.1 points per game with a +781 scoring differential overall. It puts up 83.6 points per game (ninth in college basketball) and gives up 62.5 per contest (seventh in college basketball).
• Cooper Flagg's 19 points per game lead Duke and are 42nd in the nation.
• Alabama has a +368 scoring differential, topping opponents by 10.2 points per game. It is putting up 91.4 points per game, first in college basketball, and is allowing 81.2 per outing to rank 356th in college basketball.
• Alabama's leading scorer, Mark Sears, is 42nd in the country, averaging 19 points per game.
• The Blue Devils grab 35.7 rebounds per game (24th in college basketball) while allowing 27.1 per contest to their opponents. They outrebound opponents by 8.6 boards per game.
• Flagg's 7.5 rebounds per game lead the Blue Devils and rank 104th in college basketball action.
• The Crimson Tide come out on top in the rebound battle by an average of 6.2 boards. They are collecting 39.1 rebounds per game (second in college basketball) compared to their opponents' 32.9.
• Grant Nelson averages 7.6 rebounds per game (90th in college basketball) to lead the Crimson Tide.
• Duke ranks first in college basketball by averaging 111.4 points per 100 possessions on offense, and defensively is sixth in college basketball, allowing 83.3 points per 100 possessions.
• The Crimson Tide average 105.1 points per 100 possessions on offense (15th in college basketball), and concede 93.4 points per 100 possessions (169th in college basketball).

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