Diamondbacks vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 19

Odds updated as of 5:19 a.m.

MLB action on Friday includes the Arizona Diamondbacks playing the Philadelphia Phillies.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs Phillies Game Info

• Arizona Diamondbacks (77-76) vs. Philadelphia Phillies (91-62)
• Date: Friday, September 19, 2025
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: MLB Network, ARID, and NBCS-PH

Diamondbacks vs Phillies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-120) | PHI: (+102)
• Spread: ARI: -1.5 (+162) | PHI: +1.5 (-196)
• Total: 9.5 -- Over: (+104) | Under: (-128)

Diamondbacks vs Phillies Probable Starting Pitchers

Probable Pitchers: Ryne Nelson (Diamondbacks) - 7-3, 3.34 ERA vs Taijuan Walker (Phillies) - 5-8, 4.17 ERA

The Diamondbacks will give the nod to Ryne Nelson (7-3, 3.34 ERA), who is eyeing win No. 8 on the season, and the Phillies will counter with Taijuan Walker (5-8, 4.17 ERA). When Nelson starts, his team is 12-9-0 against the spread this season. Nelson's team is 6-4 this season when he starts and they are the moneyline favorite. The Phillies have a 10-8-0 record against the spread in Walker's starts. The Phillies have been the moneyline underdog in six of Walker's starts this season, and they went 4-2 in those games.

Diamondbacks vs Phillies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (55%)

Diamondbacks vs Phillies Moneyline

• Philadelphia is a +102 underdog on the moneyline, while Arizona is a -120 favorite at home.

Diamondbacks vs Phillies Spread

• The Phillies are at +1.5 on the runline against the Diamondbacks. The Phillies are -196 to cover the spread, and the Diamondbacks are +162.

Diamondbacks vs Phillies Over/Under

• The Diamondbacks-Phillies contest on Sept. 19 has been given an over/under of 9.5 runs. The over is set at +104 and the under at -128.

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Diamondbacks vs Phillies Betting Trends

• The Diamondbacks have been chosen as favorites in 83 games this year and have walked away with the win 44 times (53%) in those games.
• This year Arizona has won 30 of 61 games when listed as at least -120 on the moneyline.
• The Diamondbacks and their opponents have gone over in 74 of their 149 games with a total set by sportsbooks this season.
• The Diamondbacks are 74-75-0 against the spread in their 149 games that had a posted line this season.
• The Phillies have been the underdog on the moneyline 28 total times this season. They've gone 13-15 in those games.
• When playing as a moneyline underdog with odds of +102 or longer, Philadelphia has a 10-9 record (winning 52.6% of its games).
• In the 146 games bookmakers have set an over/under for the Phillies, they have combined with opponents to go over the total 61 times (61-76-9).
• The Phillies have a 76-70-0 record against the spread this season (covering 52.1% of the time).

Diamondbacks Player Leaders

• Geraldo Perdomo has an OPS of .852, fueled by an OBP of .391 to go with a slugging percentage of .461. He has a .289 batting average, as well.
• Among all qualifying hitters in baseball, he ranks 13th in batting average, fourth in on-base percentage, and 48th in slugging.
• Perdomo has picked up at least one hit in eight games in a row. In his last 10 games he is batting .333 with two doubles, a triple, two home runs, eight walks and six RBIs.
• Corbin Carroll has 139 hits, which leads Arizona batters this season. He's batting .258 with 77 extra-base hits. He's also slugging .545 with an on-base percentage of .339.
• His batting average ranks 70th among qualified players, his on-base percentage 51st, and his slugging percentage sixth.
• Carroll has picked up at least one hit in four straight games. In his last five games he is batting .333 with a double, a triple, five walks and two RBIs.
• Ketel Marte has collected 123 base hits, an OBP of .372 and a slugging percentage of .497 this season.
• Gabriel Moreno has been key for Arizona with 70 hits, an OBP of .349 plus a slugging percentage of .451.

Phillies Player Leaders

• Kyle Schwarber has put up a team-high OBP (.370), while pacing the Phillies in hits (138). He's batting .243 and slugging.
• Including all qualified hitters, he ranks 102nd in batting average, while his on-base percentage is 12th and he is fourth in slugging.
• Bryce Harper is batting .263 with 32 doubles, 27 home runs and 66 walks. He's slugging .501 with an on-base percentage of .358.
• Including all qualified hitters, he is 54th in batting average, 25th in on-base percentage and 15th in slugging percentage.
• Bryson Stott is hitting .257 with 20 doubles, three triples, 12 home runs and 52 walks.
• Nick Castellanos has 27 doubles, two triples, 16 home runs and 31 walks while hitting .252.

Diamondbacks vs Phillies Head to Head

• 5/4/2025: 11-9 ARI (Favorite: Phillies, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 5/3/2025: 7-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/2/2025: 3-2 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/11/2024: 12-5 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/10/2024: 11-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 3-2 ARI (Favorite: Phillies, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/8/2024: 6-4 PHI (Favorite: Diamondbacks, Spread: -1.5, Total: 10.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 6/23/2024: 4-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 6/22/2024: 12-1 PHI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 6/21/2024: 5-4 ARI (Favorite: Phillies, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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