Diamondbacks vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 4:11 a.m.

The MLB's Thursday slate includes the Arizona Diamondbacks facing the San Diego Padres.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Diamondbacks vs Padres Game Info

• Arizona Diamondbacks (61-54) vs. San Diego Padres (59-56)
• Date: Thursday, August 6, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and Padres.TV

Diamondbacks vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-116) | SD: (-102)
• Spread: ARI: +1.5 (-200) | SD: -1.5 (+164)
• Total: 9 -- Over: (-104) | Under: (-118)

Diamondbacks vs Padres Probable Starting Pitchers

Probable Pitchers: Kohl Drake (Diamondbacks) - 0-0, 4.85 ERA vs Walker Buehler (Padres) - 6-5, 5.18 ERA

The probable pitchers are Kohl Drake for the Diamondbacks and Walker Buehler (6-5) for the Padres. Drake and his team have a record of 1-2-0 against the spread when he starts. Drake's team is 1-1 this season when he starts and they're favored on the moneyline. The Padres have gone 15-7-0 ATS in Buehler's 22 starts with a set spread. The Padres have a 9-4 record in Buehler's 13 starts this season when they were the underdog on the moneyline.

Diamondbacks vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (54.2%)

Diamondbacks vs Padres Moneyline

• The moneyline numbers for Diamondbacks vs. Padres reveal Arizona as the favorite (-116) and San Diego as the underdog (-102) on the road.

Diamondbacks vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Diamondbacks. The Padres are +164 to cover, while the Diamondbacks are -200 to cover as a 1.5-run underdog on the runline.

Diamondbacks vs Padres Over/Under

• The over/under for Diamondbacks-Padres on Aug. 6 is 9. The over is -104, and the under is -118.

Bet on Arizona Diamondbacks vs. San Diego Padres on FanDuel today!

Diamondbacks vs Padres Betting Trends

• The Diamondbacks have won in 29, or 60.4%, of the 48 contests they have been named as odds-on favorites in this year.
• Arizona has a record of 24-15 in contests when oddsmakers favor them by -116 or more on the moneyline.
• The Diamondbacks and their opponents have gone over the total this season in 49 of their 114 opportunities.
• The Diamondbacks are 61-53-0 against the spread in their 114 games with a line set by sportsbooks this season.
• The Padres have been the moneyline underdog 63 total times this season. They've gone 30-33 in those games.
• When it has played as a moneyline underdog with odds of -102 or longer, San Diego has a 26-33 record (winning 44.1% of its games).
• The Padres have played in 115 games with an over/under set, and have combined with their opponents to go over the total 53 times (53-61-1).
• The Padres have gone 63-52-0 against the spread this season.

Diamondbacks Player Leaders

• Corbin Carroll has 102 hits, which ranks first among Arizona hitters this season, while batting .245 with 50 extra-base hits. He has an on-base percentage of .340 and a slugging percentage of .470.
• Among all qualified hitters in MLB, he ranks 90th in batting average, 59th in on-base percentage, and 35th in slugging.
• Ketel Marte has an OPS of .744, fueled by an OBP of .304 and a team-best slugging percentage of .440 this season. He's batting .247.
• His batting average ranks 88th among qualified players, his on-base percentage 120th, and his slugging percentage 63rd.
• Geraldo Perdomo has collected 97 base hits, an OBP of .359 and a slugging percentage of .368 this season.
• Perdomo has logged a hit or more in six games in a row. During his last 10 outings he is hitting .349 with a triple, two home runs, five walks and five RBIs.
• Ildemaro Vargas has seven home runs, 55 RBI and a batting average of .274 this season.

Padres Player Leaders

• Fernando Tatis Jr. has accumulated a .349 on-base percentage and a .402 slugging percentage, both team-best averages for the Padres. He's batting .280.
• Including all the qualifying hitters in MLB, he is 32nd in batting average, 48th in on-base percentage and 97th in slugging percentage.
• Manny Machado leads his team with 88 hits. He has a batting average of .212 while slugging .427 with an on-base percentage of .295.
• He is 140th in batting average, 131st in on-base percentage and 72nd in slugging percentage in MLB.
• Jackson Merrill is batting .240 with 18 doubles, a triple, 16 home runs and 31 walks.
• Xander Bogaerts has 11 doubles, nine home runs and 52 walks while batting .223.

Diamondbacks vs Padres Head to Head

• 8/5/2026: 10-4 ARI (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +122)
• 8/4/2026: 9-4 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -114, Underdog Moneyline: +104)
• 8/3/2026: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 7/9/2026: 3-1 ARI (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 7/8/2026: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/7/2026: 4-1 SD (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/6/2026: 8-0 ARI (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/26/2026: 12-7 ARI (Favorite: Padres, Spread: -1.5, Total: 15, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/25/2026: 6-4 SD (Favorite: Diamondbacks, Spread: -1.5, Total: 16, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/28/2025: 12-4 SD (Favorite: Padres, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)

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