Cubs vs Phillies Prediction, Odds, Moneyline, Spread & Over/Under for April 25

Odds updated as of 1:11 a.m.

The Chicago Cubs are among the MLB teams in action on Friday, versus the Philadelphia Phillies.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Phillies Game Info

• Chicago Cubs (16-10) vs. Philadelphia Phillies (13-12)
• Date: Friday, April 25, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MLB Network, MARQ, and NBCS-PH

Cubs vs Phillies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-130) | PHI: (+110)
• Spread: CHC: -1.5 (+160) | PHI: +1.5 (-194)
• Total: 8 -- Over: (-115) | Under: (-105)

Cubs vs Phillies Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 0-0, 1.32 ERA vs Taijuan Walker (Phillies) - 1-1, 2.29 ERA

This contest's pitching matchup is set, as the Cubs will send Colin Rea to the mound, while Taijuan Walker (1-1) will get the nod for the Phillies. Rea has a record of 2-0-0 ATS in two starts with a spread this season. This will be Rea's first start this season with his team as the moneyline favorite. The Phillies have a 2-2-0 record against the spread in Walker's starts. The Phillies were named the moneyline underdog for one Walker start this season -- they won.

Cubs vs Phillies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (57%)

Cubs vs Phillies Moneyline

• The moneyline numbers for Cubs vs. Phillies reveal Chicago as the favorite (-130) and Philadelphia as the underdog (+110) on the road.

Cubs vs Phillies Spread

• The Cubs are favored by 1.5 runs at home versus the Phillies. The Cubs are +160 to cover the spread, while the Phillies are -194.

Cubs vs Phillies Over/Under

• A total of 8 runs has been set for the Cubs-Phillies game on April 25, with the over available at -115 and the under at -105.

Bet on Chicago Cubs vs. Philadelphia Phillies on FanDuel today!

Cubs vs Phillies Betting Trends

• The Cubs have been victorious in nine, or 81.8%, of the 11 contests they have been chosen as favorites in this season.
• Chicago has a record of 7-2 in contests when sportsbooks favor them by -130 or more on the moneyline.
• The Cubs and their opponents have gone over in 17 of their 25 games with a total set by sportsbooks this season.
• The Cubs have posted a record of 14-11-0 against the spread this season.
• The Phillies have been the moneyline underdog six total times this season. They've gone 3-3 in those games.
• Philadelphia is 1-2 (winning just 33.3% of its games) when playing as a moneyline underdog of +110 or longer.
• The Phillies have played in 25 games with an over/under set, and have combined with opponents to go over the total 12 times (12-13-0).
• The Phillies have a 13-12-0 record against the spread this season (covering 52% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.423), slugging percentage (.637) and total hits (32) this season. He has a .314 batting average.
• He ranks 19th in batting average, seventh in on-base percentage, and fifth in slugging among all qualifying batters in MLB.
• Pete Crow-Armstrong has nine doubles, a triple, five home runs and six walks. He's batting .294 and slugging .549 with an on-base percentage of .339.
• Among qualifying hitters, he ranks 35th in batting average, 67th in on-base percentage and 18th in slugging percentage.
• Crow-Armstrong heads into this game looking to extend his two-game hit streak. During his last five outings he is batting .429 with three doubles, two home runs, a walk and seven RBI.
• Carson Kelly is batting .342 with a .895 slugging percentage and 18 RBI this year.
• Ian Happ has been key for Chicago with 30 hits, an OBP of .352 plus a slugging percentage of .366.
• Happ heads into this game on a three-game hitting streak. In his last five games he is batting .409 with a double, a home run, three walks and five RBI.

Phillies Player Leaders

• Kyle Schwarber has racked up a team-high OBP (.411), and paces the Phillies in hits (23). He's batting .258 and slugging.
• Including all the qualifying hitters in the majors, his batting average places him 73rd, his on-base percentage ranks 13th, and he is 27th in slugging.
• Bryce Harper is batting .250 with four doubles, five home runs and 21 walks. He's slugging .457 with an on-base percentage of .389.
• Including all qualified players, he ranks 79th in batting average, 27th in on-base percentage and 54th in slugging percentage.
• Nicholas Alexander Castellanos has put up a slugging percentage of .440, a team-high for the Phillies.
• Bryson Stott is slugging .440 to lead his team.

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