Cubs vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for NL Wild Card Game 3 on Oct. 2

Odds updated as of 12:12 a.m.

In MLB action on Thursday, the Chicago Cubs take on the San Diego Padres for Game 3 of the NL Wild Card Series.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Padres Game Info

• Chicago Cubs (92-70) vs. San Diego Padres (90-72)
• Date: Thursday, October 2, 2025
• Time: 3:08 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: ABC

Cubs vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-118) | SD: (-100)
• Spread: CHC: +1.5 (-210) | SD: -1.5 (+172)
• Total: 7.5 -- Over: (-110) | Under: (-110)

Cubs vs Padres Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 11-7, 3.68 ERA vs Yu Darvish (Padres) - 5-5, 5.37 ERA

The probable starters are Jameson Taillon (11-7, 3.68 ERA) for the Cubs and Yu Darvish (5-5, 5.37 ERA) for the Padres. Taillon's team is 11-10-0 against the spread this season in his starts. Taillon's team has won 71.4% of his starts when they are favored on the moneyline (10-4). The Padres have a 10-4-0 record against the spread in Darvish's starts. The Padres have a 3-3 record in Darvish's six starts this season when they were the moneyline underdog.

Cubs vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.3%)

Cubs vs Padres Moneyline

• The Cubs vs Padres moneyline has Chicago as a -118 favorite, while San Diego is a -100 underdog on the road.

Cubs vs Padres Spread

• The Padres are 1.5-run favorites against the spread for this matchup with the Cubs. The Padres are +172 to cover, while the Cubs are -210 to cover as a 1.5-run underdog on the runline.

Cubs vs Padres Over/Under

• Cubs versus Padres on Oct. 2 has an over/under of 7.5 runs, with the odds on the over -110 and the under set at -110.

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Cubs vs Padres Betting Trends

• The Cubs have been favorites in 110 games this season and have come away with the win 71 times (64.5%) in those contests.
• This season Chicago has come away with a win 68 times in 99 chances when named as a favorite of at least -118 on the moneyline.
• Contests with the Cubs have gone over the total set by oddsmakers in 74 of 159 chances this season.
• The Cubs have an against the spread mark of 76-83-0 in 159 games with a line this season.
• The Padres have won 34 of the 69 games they were the moneyline underdog this season (49.3%).
• When playing as a moneyline underdog with odds of -100 or longer, San Diego has a 27-31 record (winning 46.6% of its games).
• The Padres have combined with opponents to hit the over on the total 70 times this season for a 70-89-3 record against the over/under.
• The Padres have put together an 88-74-0 record ATS this season (covering 54.3% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago in OBP (.377) this season, fueled by 133 hits. He has a .266 batting average and a slugging percentage of .464.
• Among qualifying hitters in MLB, his batting average ranks 46th, his on-base percentage ranks seventh, and he is 44th in slugging.
• Nico Hoerner has an OPS of .739, fueled by an OBP of .345 and a team-best slugging percentage of .394 this season. He's batting .297.
• Among qualifying batters, he is eighth in batting average, 46th in on-base percentage and 110th in slugging percentage.
• Hoerner takes a three-game streak with at least one hit into this contest. During his last five outings he is batting .286 with a home run and two RBIs.
• Pete Crow-Armstrong has 146 hits this season and has a slash line of .247/.287/.481.
• Seiya Suzuki is batting .245 with a .326 OBP and 103 RBI for Chicago this season.
• Suzuki brings a nine-game hitting streak into this game. In his last 10 outings he is hitting .294 with two doubles, six home runs, two walks and 13 RBIs.

Padres Player Leaders

• Fernando Tatis Jr. has a team-high .368 on-base percentage. He's batting .268 and slugging .446.
• He is 43rd in batting average, 10th in on-base percentage and 60th in slugging percentage among all qualified hitters in the majors.
• Manny Machado leads his team with 169 hits. He has a batting average of .275 while slugging .460 with an on-base percentage of .335.
• Including all qualified hitters, he ranks 33rd in batting average, 58th in on-base percentage and 49th in slugging percentage.
• Luis Arraez has racked up a slugging percentage of .392, a team-best for the Padres.
• Ryan O'Hearn is hitting .281 with 21 doubles, a triple, 17 home runs and 58 walks.

Cubs vs Padres Head to Head

• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/16/2025: 4-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/15/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/14/2025: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/6/2025: 8-7 SD (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/5/2025: 7-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/4/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/8/2024: 3-0 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/7/2024: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)

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