Cubs vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for July 1

Odds updated as of 11:12 p.m.

On Wednesday in MLB, the Chicago Cubs are up against the San Diego Padres.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Padres Game Info

• Chicago Cubs (47-38) vs. San Diego Padres (43-40)
• Date: Wednesday, July 1, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Padres.TV

Cubs vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-154) | SD: (+130)
• Spread: CHC: -1.5 (+128) | SD: +1.5 (-154)
• Total: 11.5 -- Over: (+104) | Under: (-128)

Cubs vs Padres Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 5-5, 4.80 ERA vs Walker Buehler (Padres) - 5-3, 3.81 ERA

The probable pitchers are Colin Rea (5-5) for the Cubs and Walker Buehler (5-3) for the Padres. Rea and his team are 3-10-0 ATS this season when he starts. Rea's team is 3-5 this season when he starts and they are the moneyline favorite. The Padres have gone 12-4-0 ATS in Buehler's 16 starts that had a set spread. The Padres have been the moneyline underdog in 10 of Buehler's starts this season, and they went 7-3 in those matchups.

Cubs vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (59.2%)

Cubs vs Padres Moneyline

• Chicago is the favorite, -154 on the moneyline, while San Diego is a +130 underdog on the road.

Cubs vs Padres Spread

• The Padres are +1.5 on the spread (-154 to cover), and Chicago is +128 to cover the runline.

Cubs vs Padres Over/Under

• The over/under for Cubs-Padres on July 1 is 11.5. The over is +104, and the under is -128.

Bet on Chicago Cubs vs. San Diego Padres on FanDuel today!

Cubs vs Padres Betting Trends

• The Cubs have been victorious in 31, or 56.4%, of the 55 contests they have been chosen as favorites in this season.
• This season Chicago has been victorious 14 times in 21 chances when named as a favorite of at least -154 on the moneyline.
• The Cubs' games have gone over the total in 44 of their 83 opportunities.
• The Cubs have posted a record of 34-49-0 against the spread this season.
• The Padres have been the underdog on the moneyline 46 total times this season. They've finished 22-24 in those games.
• San Diego has gone 2-9 in games it has played as a moneyline underdog with odds of +130 or longer (18.2%).
• The Padres have combined with opponents to go over the total 36 times this season for a 36-46-1 record against the over/under.
• The Padres have collected a 46-37-0 record ATS this season (covering 55.4% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong leads Chicago in OBP (.372), slugging percentage (.509) and total hits (91) this season. He has a .284 batting average.
• Among qualifying hitters in baseball, he is 26th in batting average, 22nd in on-base percentage, and 20th in slugging.
• Nico Hoerner is hitting .243 with 21 doubles, four home runs and 34 walks. He's slugging .342 with an on-base percentage of .319.
• He is 98th in batting average, 94th in on-base percentage and 136th in slugging among qualified batters.
• Hoerner enters this matchup looking to extend his three-game hit streak. During his last five outings he is hitting .278 with a walk and an RBI.
• Ian Happ has 67 hits this season and has a slash line of .221/.331/.452.
• Michael Busch has nine home runs, 45 RBI and a batting average of .233 this season.

Padres Player Leaders

• Manny Machado has 15 doubles, 15 home runs and 37 walks while batting .186. He's slugging .389 with an on-base percentage of .272.
• He is 153rd in batting average, 147th in on-base percentage and 106th in slugging percentage among all qualifying batters in the majors.
• Fernando Tatis Jr.'s .345 OBP and .364 slugging percentage are both team-highs. He has a batting average of .282.
• He is currently 29th in batting average, 53rd in on-base percentage and 125th in slugging percentage among all qualified batters.
• Xander Bogaerts is batting .234 with five doubles, eight home runs and 35 walks.
• Gavin Sheets paces his team with 55 hits.

Cubs vs Padres Head to Head

• 6/29/2026: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 11.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/29/2026: 5-4 CHC (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2026: 8-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/27/2026: 9-7 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/2/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/16/2025: 4-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/15/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/14/2025: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!