Cubs vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 10

Odds updated as of 6:11 a.m.

On Sunday in MLB, the Chicago Cubs are playing the St. Louis Cardinals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Cubs vs Cardinals Game Info

• Chicago Cubs (67-49) vs. St. Louis Cardinals (59-59)
• Date: Sunday, August 10, 2025
• Time: 7:10 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: ESPN

Cubs vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-120) | STL: (+102)
• Spread: CHC: -1.5 (+146) | STL: +1.5 (-178)
• Total: 8 -- Over: (-105) | Under: (-115)

Cubs vs Cardinals Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 8-4, 3.12 ERA vs Sonny Gray (Cardinals) - 10-5, 4.21 ERA

This contest's pitching matchup is set, as the Cubs will send Shota Imanaga (8-4) to the mound, while Sonny Gray (10-5) will get the nod for the Cardinals. Imanaga and his team have a record of 8-8-0 against the spread when he starts. Imanaga's team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 6-4. The Cardinals have gone 12-10-0 ATS in Gray's 22 starts that had a set spread. The Cardinals are 5-2 in Gray's seven starts this season that they were the moneyline underdog.

Cubs vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (53%)

Cubs vs Cardinals Moneyline

• Chicago is a -120 favorite on the moneyline, while St. Louis is a +102 underdog at home.

Cubs vs Cardinals Spread

• The Cardinals are at +1.5 on the runline against the Cubs. The Cardinals are -178 to cover the spread, and the Cubs are +146.

Cubs vs Cardinals Over/Under

• An over/under of 8 has been set for Cubs-Cardinals on Aug. 10, with the over being -105 and the under -115.

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Cubs vs Cardinals Betting Trends

• The Cubs have been victorious in 51, or 66.2%, of the 77 contests they have been chosen as favorites in this season.
• Chicago has a record of 47-22 when favored by -120 or more this year.
• The Cubs and their opponents have hit the over in 56 of their 113 games with a total set by oddsmakers this season.
• In 113 games with a line this season, the Cubs have a mark of 54-59-0 against the spread.
• The Cardinals have compiled a 31-31 record in games they were the underdog on the moneyline (winning 50% of those games).
• When playing as a moneyline underdog with odds of +102 or longer, St. Louis has gone 18-24 (42.9%).
• The Cardinals have combined with opponents to hit the over on the total 58 times this season for a 58-52-5 record against the over/under.
• The Cardinals have a 60-55-0 record against the spread this season (covering 52.2% of the time).

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .386 this season while batting .272 with 76 walks and 77 runs scored. He has a slugging percentage of .471.
• Among qualified hitters, he is 49th in batting average, his on-base percentage ranks fifth, and he is 37th in slugging.
• Tucker hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .235 with two walks and an RBI.
• Pete Crow-Armstrong leads Chicago in total hits (115) this season while batting .258 with 62 extra-base hits. He's slugging .528 with an on-base percentage of .295.
• Among qualified hitters, he ranks 77th in batting average, 140th in on-base percentage and 10th in slugging percentage.
• Seiya Suzuki has collected 109 base hits, an OBP of .318 and a slugging percentage of .510 this season.
• Suzuki has picked up a hit in three games in a row. During his last five outings he is batting .353 with a double, a home run, three walks and three RBIs.
• Nico Hoerner has an OPS of .715, fueled by an OBP of .338 and a team-best slugging percentage of .376 this season.

Cardinals Player Leaders

• Brendan Donovan has accumulated a team-high OBP (.349) and slugging percentage (.402). He's batting .278.
• Including all the qualified hitters in MLB, he is 32nd in batting average, 44th in on-base percentage and 102nd in slugging percentage.
• Alec Burleson has 19 doubles, 14 home runs and 31 walks while batting .282. He's slugging .449 with an on-base percentage of .337.
• He is currently 26th in batting average, 62nd in on-base percentage and 64th in slugging percentage among all qualified batters.
• Willson Contreras has racked up 105 hits, a team-high for the Cardinals.
• Masyn Winn is hitting .269 with 25 doubles, eight home runs and 29 walks.

Cubs vs Cardinals Head to Head

• 8/9/2025: 9-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 8/8/2025: 5-0 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 7/5/2025: 8-6 STL (Favorite: Cubs, Spread: -1.5, Total: 11, Favorite Moneyline: -164, Underdog Moneyline: +138)
• 7/4/2025: 11-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/26/2025: 3-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/25/2025: 8-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/24/2025: 8-7 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/23/2025: 8-2 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/4/2024: 6-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 9, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 8/3/2024: 5-4 STL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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