Cubs vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 3 on Oct. 8

Odds updated as of 2:15 a.m.

The Chicago Cubs versus the Milwaukee Brewers in Game 3 of the NLDS is on the MLB schedule for Wednesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this game.

Cubs vs Brewers Game Info

• Chicago Cubs (92-70) vs. Milwaukee Brewers (97-65)
• Date: Wednesday, October 8, 2025
• Time: 5:08 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: truTV, TBS, and HBO Max

Cubs vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-120) | MIL: (+102)
• Spread: CHC: +1.5 (-220) | MIL: -1.5 (+180)
• Total: 6.5 -- Over: (-118) | Under: (-104)

Cubs vs Brewers Probable Starting Pitchers

Probable Pitchers: Jameson Taillon (Cubs) - 11-7, 3.68 ERA vs Quinn Priester (Brewers) - 13-3, 3.32 ERA

The probable pitchers are Jameson Taillon (11-7, 3.68 ERA) for the Cubs and Quinn Priester (13-3, 3.32 ERA) for the Brewers. Taillon's team is 12-10-0 against the spread this season in his starts. Taillon's team is 11-4 this season when he starts and they are the moneyline favorite. The Brewers have a 15-9-0 record against the spread in Priester's starts. The Brewers have been the underdog on the moneyline in 11 of Priester's starts this season, and they went 7-4 in those matchups.

Cubs vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (57.7%)

Cubs vs Brewers Moneyline

• The moneyline numbers for Cubs vs. Brewers reveal Chicago as the favorite (-120) and Milwaukee as the underdog (+102) on the road.

Cubs vs Brewers Spread

• The Brewers are 1.5-run favorites against the spread for this matchup with the Cubs. The Brewers are +180 to cover, while the Cubs are -220 to cover as a 1.5-run underdog on the runline.

Cubs vs Brewers Over/Under

• The Cubs-Brewers contest on Oct. 8 has been given an over/under of 6.5 runs. The over is set at -118 and the under at -104.

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Cubs vs Brewers Betting Trends

• The Cubs have been chosen as favorites in 111 games this year and have walked away with the win 72 times (64.9%) in those games.
• This season Chicago has been victorious 66 times in 96 chances when named as a favorite of at least -120 on the moneyline.
• The Cubs and their opponents have gone over the total this season in 76 of their 162 opportunities.
• The Cubs are 77-85-0 against the spread in their 162 games that had a posted line this season.
• The Brewers have been the underdog on the moneyline 60 total times this season. They've gone 34-26 in those games.
• Milwaukee has a 25-23 record (winning 52.1% of its games) when playing as a moneyline underdog of +102 or longer.
• The Brewers have played in 161 games with a set over/under, and have combined with their opponents to go over the total 81 times (81-78-2).
• The Brewers are 89-72-0 ATS this season.

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .377 this season while batting .266 with 87 walks and 91 runs scored. He has a slugging percentage of .464.
• Among all qualifying hitters, he is 46th in batting average, his on-base percentage ranks seventh, and he is 44th in slugging.
• Nico Hoerner has hit seven homers this season while driving in 61 runs. He's batting .297 this season and slugging .394 with an on-base percentage of .345.
• His batting average is eighth among qualified players, his on-base percentage 46th, and his slugging percentage 110th.
• Hoerner enters this game looking to extend his six-game hit streak. During his last 10 outings he is hitting .268 with a double, two home runs, a walk and three RBIs.
• Pete Crow-Armstrong has 146 hits this season and has a slash line of .247/.287/.481.
• Seiya Suzuki has 32 home runs, 103 RBI and a batting average of .245 this season.

Brewers Player Leaders

• Brice Turang has put up an on-base percentage of .359 and a slugging percentage of .435. Both lead the Brewers. He's batting .288.
• Including all qualifying players in the majors, he ranks 16th in batting average, 20th in on-base percentage and 71st in slugging percentage.
• Christian Yelich has 21 doubles, 29 home runs and 64 walks while batting .264. He's slugging .452 with an on-base percentage of .343.
• He is 51st in batting average, 49th in on-base percentage and 56th in slugging percentage in the majors.
• William Contreras is hitting .260 with 28 doubles, 17 home runs and 84 walks.
• Jackson Chourio's 148 hits pace his team.

Cubs vs Brewers Head to Head

• 10/6/2025: 7-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)

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