Cubs vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 2:11 a.m.

The Chicago Cubs will face the Milwaukee Brewers in MLB action on Wednesday.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Brewers Game Info

• Chicago Cubs (29-20) vs. Milwaukee Brewers (28-18)
• Date: Wednesday, May 20, 2026
• Time: 7:40 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Brewers.TV

Cubs vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-120) | MIL: (+102)
• Spread: CHC: +1.5 (-230) | MIL: -1.5 (+188)
• Total: 6.5 -- Over: (+102) | Under: (-124)

Cubs vs Brewers Probable Starting Pitchers

Probable Pitchers: Edward Cabrera (Cubs) - 3-1, 4.06 ERA vs Kyle Harrison (Brewers) - 4-1, 2.09 ERA

The Cubs will look to Edward Cabrera (3-1) versus the Brewers and Kyle Harrison (4-1). Cabrera's team is 5-3-0 against the spread in his starts this season. Cabrera's team has a record of 5-2 this season when he starts and they are the favorite on the moneyline. The Brewers are 6-2-0 ATS in Harrison's eight starts that had a set spread. The Brewers were the moneyline underdog for three Harrison starts this season -- they won each time.

Cubs vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (55%)

Cubs vs Brewers Moneyline

• Chicago is a -120 favorite on the moneyline, while Milwaukee is a +102 underdog on the road.

Cubs vs Brewers Spread

• The Brewers are 1.5-run favorites against the spread for this matchup with the Cubs. The Brewers are +188 to cover, while the Cubs are -230 to cover as a 1.5-run underdog on the runline.

Cubs vs Brewers Over/Under

• The Cubs-Brewers contest on May 20 has been given an over/under of 6.5 runs. The over is set at +102 and the under at -124.

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Cubs vs Brewers Betting Trends

• The Cubs have been victorious in 20, or 64.5%, of the 31 contests they have been chosen as favorites in this season.
• Chicago has a record of 17-10 in contests when oddsmakers favor them by -120 or more on the moneyline.
• The Cubs and their opponents have hit the over in 28 of their 48 games with a total set by oddsmakers this season.
• The Cubs are 21-27-0 against the spread in their 48 games that had a posted line this season.
• The Brewers have compiled a 9-7 record in games they were the underdog on the moneyline (winning 56.2% of those games).
• Milwaukee is 4-4 (winning 50% of its games) when it has played as a moneyline underdog of +102 or longer.
• The Brewers have played in 46 games with an over/under set, and have combined with their opponents to go over the total 21 times (21-23-2).
• The Brewers have a 28-18-0 record ATS this season.

Cubs Player Leaders

• Nico Hoerner has an OPS of .738, fueled by an OBP of .350 and a team-best slugging percentage of .389 this season. He has a .264 batting average.
• Among qualifying batters in baseball, he ranks 59th in batting average, 58th in on-base percentage, and 100th in slugging.
• Dansby Swanson is batting .195 with four doubles, a triple, seven home runs and 24 walks, while slugging .365 with an on-base percentage of .299.
• His batting average is 159th among qualified players, his on-base percentage 129th, and his slugging percentage 125th.
• Swanson takes a four-game streak with at least one hit into this matchup. During his last five outings he is hitting .200 with a double, a home run, a walk and two RBIs.
• Ian Happ has collected 38 base hits, an OBP of .358 and a slugging percentage of .437 this season.
• Michael Busch is batting .236 with a .360 OBP and 27 RBI for Chicago this season.

Brewers Player Leaders

• Brice Turang has accumulated an on-base percentage of .413, a team-best for the Brewers. He's batting .292 and slugging .497.
• Including all the qualified players in the majors, he ranks 25th in batting average, fifth in on-base percentage and 28th in slugging percentage.
• William Contreras leads his team with a .375 slugging percentage. He has a batting average of .278 with an on-base percentage of .350.
• He is 41st in batting average, 58th in on-base percentage and 116th in slugging percentage in the majors.
• Jake Bauers has accumulated 42 hits, a team-high for the Brewers.
• Sal Frelick is hitting .227 with four doubles, three home runs and 16 walks.

Cubs vs Brewers Head to Head

• 5/19/2026: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/18/2026: 9-3 MIL (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 10/11/2025: 3-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 10/9/2025: 6-0 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 10/8/2025: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 10/6/2025: 7-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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