Top 25 College Basketball Picks & Predictions Today - March 22

The men's college basketball slate on Saturday features nine games involving Top 25 teams in the AP Poll, with No. 2 Houston playing No. 24 Gonzaga at 8:40 p.m. ET being one of the day's more intriguing matchups. Keep reading for picks and predictions for each matchup.

Ahead of today's March Madness action, here's an in-depth look at the betting odds.

Purdue vs. McNeese

• Matchup: McNeese Cowboys vs. No. 22 Purdue Boilermakers
• Projected Winner: Purdue (53.24% win probability)
• Spread: Purdue (-5.5)
• Time: 12:10 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Purdue vs. McNeese with FanDuel Sportsbook.

St. John's vs. Arkansas

• Matchup: Arkansas Razorbacks vs. No. 5 St. John's Red Storm
• Projected Winner: St. John's (69.51% win probability)
• Spread: St. John's (-7.5)
• Time: 2:40 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on St. John's vs. Arkansas with FanDuel Sportsbook.

Texas A&M vs. Michigan

• Matchup: No. 14 Michigan Wolverines vs. No. 19 Texas A&M Aggies
• Projected Winner: Texas A&M (56.31% win probability)
• Spread: Texas A&M (-2.5)
• Time: 5:15 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Texas A&M vs. Michigan with FanDuel Sportsbook.

Texas A&M vs. Michigan

• Matchup: No. 14 Michigan Wolverines vs. No. 19 Texas A&M Aggies
• Projected Winner: Texas A&M (54.31% win probability)
• Spread: Texas A&M (-2.5)
• Time: 5:15 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Texas A&M vs. Michigan with FanDuel Sportsbook.

Texas Tech vs. Drake

• Matchup: Drake Bulldogs vs. No. 9 Texas Tech Red Raiders
• Projected Winner: Texas Tech (59.77% win probability)
• Spread: Texas Tech (-6.5)
• Time: 6:10 p.m. ET
• Date: March 22
• TV Channel: TNT

Bet on Texas Tech vs. Drake with FanDuel Sportsbook.

Auburn vs. Creighton

• Matchup: Creighton Bluejays vs. No. 4 Auburn Tigers
• Projected Winner: Auburn (70.94% win probability)
• Spread: Auburn (-8.5)
• Time: 7:10 p.m. ET
• Date: March 22
• TV Channel: TBS

Bet on Auburn vs. Creighton with FanDuel Sportsbook.

Wisconsin vs. BYU

• Matchup: No. 17 BYU Cougars vs. No. 13 Wisconsin Badgers
• Projected Winner: Wisconsin (62.17% win probability)
• Spread: Wisconsin (-1.5)
• Time: 7:45 p.m. ET
• Date: March 22
• TV Channel: CBS

Bet on Wisconsin vs. BYU with FanDuel Sportsbook.

Houston vs. Gonzaga

• Matchup: No. 24 Gonzaga Bulldogs vs. No. 2 Houston Cougars
• Projected Winner: Houston (64.88% win probability)
• Spread: Houston (-5.5)
• Time: 8:40 p.m. ET
• Date: March 23
• TV Channel: TNT

Bet on Houston vs. Gonzaga with FanDuel Sportsbook.

Tennessee vs. UCLA

• Matchup: UCLA Bruins vs. No. 6 Tennessee Volunteers
• Projected Winner: Tennessee (68.32% win probability)
• Spread: Tennessee (-5.5)
• Time: 9:40 p.m. ET
• Date: March 23
• TV Channel: TBS

Bet on Tennessee vs. UCLA with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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