Auburn vs Creighton Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament Second Round

The No. 1 seed Auburn Tigers (29-5) and the No. 9 seed Creighton Bluejays (25-10) will meet in the NCAA Tournament with a spot in the Sweet 16 of the South Region bracket up for grabs on Saturday at Rupp Arena, beginning at 7:10 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Auburn vs. Creighton Game Info and Odds

• Game day: Saturday, March 22, 2025
• Game time: 7:10 p.m. ET
• TV channel: TBS
• Location: Lexington, Kentucky
• Arena: Rupp Arena

Auburn vs. Creighton Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Auburn win (70.4%)

Before you wager on Saturday's Auburn-Creighton spread (Auburn -8.5) or total (149.5 points), see the betting insights and trends below.

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Auburn vs. Creighton: ATS Betting Stats and Trends

• Auburn is 18-16-0 ATS this season.
• Creighton has put together a 22-13-0 record against the spread this year.
• As an 8.5-point underdog or more in 2024-25, Creighton is 2-0 against the spread compared to the 12-9 ATS record Auburn puts up as an 8.5-point favorite.
• The Tigers own a better record against the spread at home (8-7-0) than they do in away games (5-5-0).
• Against the spread, the Bluejays have had better results away (9-2-0) than at home (11-6-0).

Auburn vs. Creighton: Moneyline Betting Stats

• Auburn has won in 25, or 86.2%, of the 29 contests it has been named as the moneyline favorite in this year.
• The Tigers have a mark of 17-1 in contests where oddsmakers favor them by -400 or better on the moneyline.
• Creighton has won five of the 11 games it was the underdog on the moneyline this season (45.5%).
• The Bluejays have played as a moneyline underdog of +310 or longer in just two games this season, which they lost both.
• The moneyline set for this matchup implies Auburn has a 80% chance of walking away with the win.

Auburn vs. Creighton Head-to-Head Comparison

• Auburn outscores opponents by 14.4 points per game (scoring 83.8 per game to rank 10th in college basketball while giving up 69.4 per outing to rank 91st in college basketball) and has a +490 scoring differential overall.
• Johni Broome's team-leading 18.7 points per game ranks 57th in college basketball.
• Creighton puts up 75.6 points per game (126th in college basketball) while allowing 69.7 per contest (102nd in college basketball). It has a +208 scoring differential and outscores opponents by 5.9 points per game.
• Ryan Kalkbrenner's 19.2 points per game paces Creighton and ranks 33rd in the country.
• The Tigers are 60th in the country at 34.3 rebounds per game. That's 4.9 more than the 29.4 their opponents average.
• Broome averages 10.6 rebounds per game (ranking eighth in college basketball) to lead the Tigers.
• The Bluejays come out on top in the rebound battle by an average of 3.6 boards. They are recording 34.7 rebounds per game (44th in college basketball) compared to their opponents' 31.1.
• Kalkbrenner averages 8.7 rebounds per game (40th in college basketball) to lead the Bluejays.
• Auburn's 107 points per 100 possessions on offense rank sixth in college basketball, and the 88.6 points it allows per 100 possessions rank 63rd in college basketball.
• The Bluejays score 99.3 points per 100 possessions (91st in college basketball), while giving up 91.5 points per 100 possessions (128th in college basketball).

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