Top 25 College Basketball Picks & Predictions Today - December 21

The men's college basketball slate on Sunday features nine games involving Top 25 teams in the AP Poll, with No. 2 Michigan taking on La Salle at 4 p.m. ET being one of the day's more notable matchups. Continue reading for picks and predictions for each game.

Here is the betting info to break down prior to Sunday in college basketball.

Florida vs. Colgate

• Matchup: Colgate Raiders at No. 23 Florida Gators
• Projected Winner: Florida (92.77% win probability)
• Spread: Florida (-29.5)
• Time: 12 p.m. ET
• Date: December 21
• TV Channel: SEC Network+

Bet on Florida vs. Colgate with FanDuel Sportsbook.

Wake Forest vs. Vanderbilt

• Matchup: No. 13 Vanderbilt Commodores at Wake Forest Demon Deacons
• Projected Winner: Vanderbilt (55.68% win probability)
• Spread: Vanderbilt (-4.5)
• Time: 1 p.m. ET
• Date: December 21
• TV Channel: The CW Network

Bet on Wake Forest vs. Vanderbilt with FanDuel Sportsbook.

Alabama vs. Kennesaw State

• Matchup: Kennesaw State Owls vs. No. 16 Alabama Crimson Tide
• Projected Winner: Alabama (82.60% win probability)
• Spread: Alabama (-21.5)
• Time: 2 p.m. ET
• Date: December 21
• TV Channel: SEC Network+

Bet on Alabama vs. Kennesaw State with FanDuel Sportsbook.

Tennessee vs. Gardner-Webb

• Matchup: Gardner-Webb Runnin' Bulldogs at No. 20 Tennessee Volunteers
• Projected Winner: Tennessee (99.16% win probability)
• Spread: Tennessee (-40.5)
• Time: 3 p.m. ET
• Date: December 21
• TV Channel: SEC Network+

Bet on Tennessee vs. Gardner-Webb with FanDuel Sportsbook.

Michigan vs. La Salle

• Matchup: La Salle Explorers at No. 2 Michigan Wolverines
• Projected Winner: Michigan (98.47% win probability)
• Spread: Michigan (-38.5)
• Time: 4 p.m. ET
• Date: December 21
• TV Channel: Peacock

Bet on Michigan vs. La Salle with FanDuel Sportsbook.

DePaul vs. UConn

• Matchup: No. 5 UConn Huskies at DePaul Blue Demons
• Projected Winner: UConn (80.37% win probability)
• Spread: UConn (-14.5)
• Time: 4:30 p.m. ET
• Date: December 21
• TV Channel: Fox Sports 1

Bet on DePaul vs. UConn with FanDuel Sportsbook.

Oregon vs. Gonzaga

• Matchup: No. 7 Gonzaga Bulldogs vs. Oregon Ducks
• Projected Winner: Gonzaga (82.10% win probability)
• Spread: Gonzaga (-12.5)
• Time: 6 p.m. ET
• Date: December 21
• TV Channel: Peacock

Bet on Oregon vs. Gonzaga with FanDuel Sportsbook.

Iowa State vs. Long Beach State

• Matchup: Long Beach State Beach at No. 4 Iowa State Cyclones
• Projected Winner: Iowa State (98.78% win probability)
• Spread: Iowa State (-36.5)
• Time: 6 p.m. ET
• Date: December 21
• TV Channel: ESPN+

Bet on Iowa State vs. Long Beach State with FanDuel Sportsbook.

Nebraska vs. North Dakota

• Matchup: North Dakota Fightin' Hawks at No. 15 Nebraska Cornhuskers
• Projected Winner: Nebraska (97.99% win probability)
• Spread: Nebraska (-29.5)
• Time: 8 p.m. ET
• Date: December 22
• TV Channel: BTN

Bet on Nebraska vs. North Dakota with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

For more college basketball betting insights, check out FanDuel Research's college basketball home page.

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