Top 25 College Basketball Picks & Predictions Today - January 21

A matchup between No. 1 Arizona and Cincinnati at 9 p.m. ET is one of the highlights of Wednesday's slate, which features five games involving teams ranked in the AP Poll's Top 25. For picks and predictions for each matchup, continue reading.

With Wednesday's college basketball upon us, stay on top of the most current betting trends with our preview below.

North Carolina vs. Notre Dame

• Matchup: Notre Dame Fighting Irish at No. 22 North Carolina Tar Heels
• Projected Winner: North Carolina (81.68% win probability)
• Spread: North Carolina (-11.5)
• Time: 7 p.m. ET
• Date: January 22
• TV Channel: ESPN2

Bet on North Carolina vs. Notre Dame with FanDuel Sportsbook.

Illinois vs. Maryland

• Matchup: Maryland Terrapins at No. 11 Illinois Fighting Illini
• Projected Winner: Illinois (97.64% win probability)
• Spread: Illinois (-18.5)
• Time: 7 p.m. ET
• Date: January 22
• TV Channel: BTN

Bet on Illinois vs. Maryland with FanDuel Sportsbook.

Gonzaga vs. Pepperdine

• Matchup: Pepperdine Waves at No. 8 Gonzaga Bulldogs
• Projected Winner: Gonzaga (99.25% win probability)
• Spread: Gonzaga (-29.5)
• Time: 9 p.m. ET
• Date: January 22
• TV Channel: ESPN+

Bet on Gonzaga vs. Pepperdine with FanDuel Sportsbook.

Arizona vs. Cincinnati

• Matchup: Cincinnati Bearcats at No. 1 Arizona Wildcats
• Projected Winner: Arizona (85.07% win probability)
• Spread: Arizona (-13.5)
• Time: 9 p.m. ET
• Date: January 22
• TV Channel: Fox Sports 1

Bet on Arizona vs. Cincinnati with FanDuel Sportsbook.

Nebraska vs. Washington

• Matchup: Washington Huskies at No. 7 Nebraska Cornhuskers
• Projected Winner: Nebraska (85.79% win probability)
• Spread: Nebraska (-11.5)
• Time: 9 p.m. ET
• Date: January 22
• TV Channel: BTN

Bet on Nebraska vs. Washington with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

For more college basketball betting insights, check out FanDuel Research's college basketball home page.

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