Colgate vs Central Michigan Prediction, College Football Picks, Odds & Best Bets Today

College Football Betting Picks in Summary

• Central Michigan -19.5
• Over 49.5
• Central Michigan Over 221.5 Rushing Yards

Colgate travels to Central Michigan Saturday afternoon in a real, decisive mismatch — a -1800 moneyline backed by one of the higher totals on the board.

All college football odds come from FanDuel Sportsbook's college football betting odds and may change after this article is published.

College Football Predictions and Picks

Colgate at Central Michigan (Sat, 1:00 p.m. ET)

Central Michigan -19.5 (-110)

Central Michigan's own first-half spread alone sits at -10.5, more than half the full-game number — a real sign the Chippewas are expected to build a genuine lead early against an FCS opponent.

Over 49.5 (-105)

Central Michigan's own projected yardage output (422.5) is enough on its own to threaten this total, regardless of how much Colgate is able to produce on the other side.

Central Michigan Over 221.5 Rushing Yards (-113)

Central Michigan's rushing attack alone accounts for the majority of its own team yardage total, a genuine sign the Chippewas plan to establish the ground game against an outmatched FCS front.