Cavaliers vs. Clippers Prediction, Odds, Picks, Best Bets for Nov. 23

Cavaliers vs. Clippers Game Info

• Date: Sunday, November 23, 2025
• Time: 6 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: FDSOH and FDSSC

A pair of the league's best scorers hit the court when Donovan Mitchell (fifth, 30.3 PPG) and the Cleveland Cavaliers (11-6) host James Harden (ninth, 28.4 PPG) and the Los Angeles Clippers (5-11) on Sunday, November 23, 2025 at 6 p.m. ET on FDSOH and FDSSC. The Cavaliers are 9.5-point favorites. The matchup has an over/under set at 229.5 points.

Cavaliers vs. Clippers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Clippers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (79.8%)

Cavaliers vs. Clippers Betting Trends

• The Cavaliers are 6-11-0 against the spread this season.
• In the Clippers' 16 games this year, they have five wins against the spread.
• Games involving the Cavaliers have hit the over eight times out of 16 chances this season.
• Clippers games this year have hit the over on 10 of 16 set point totals (62.5%).
• At home, Cleveland has a worse record against the spread (3-7-0) compared to its ATS record on the road (3-4-0).
• When playing at home, the Cavaliers eclipse the total 30% of the time (three of 10 games). They hit the over more consistently on the road, exceeding the total in 71.4% of games (five of seven).
• This year, Los Angeles is 1-7-0 at home against the spread (.125 winning percentage). Away, it is 4-4-0 ATS (.500).
• Looking at the over/under, Clippers games have gone over 62.5% of the time this season, both at home (five of eight) and on the road (five of eight).

Cavaliers Leaders

• Mitchell is averaging 30.3 points, 5.3 assists and 4.8 boards.
• Evan Mobley is averaging 19 points, 8.8 rebounds and 4 assists. Defensively, he averages 1.1 steals and 1.6 blocked shots (eighth in NBA).
• Jarrett Allen averages 14.8 points, 7.6 boards and 1.9 assists, shooting 57.7% from the floor.
• De'Andre Hunter's numbers on the season are 18.1 points, 4.9 rebounds and 2.7 assists per game, shooting 45.3% from the field and 31.3% from downtown, with an average of 2.1 made treys.
• Jaylon Tyson is averaging 11.3 points, 1.9 assists and 4.3 rebounds.

Clippers Leaders

• Harden is averaging 28.4 points, 6 boards and 8.5 assists for the Clippers.
• The Clippers get 16 points per game from Ivica Zubac, plus 11.2 boards and 2.3 assists.
• Per game, John Collins provides the Clippers 11.6 points, 4.9 boards and 0.6 assists, plus 0.9 steals and 0.5 blocks.
• The Clippers get 6.9 points per game from Kris Dunn, plus 2.5 boards and 2.7 assists.
• Brook Lopez's numbers on the season are 6.7 points, 2 boards and 0.6 assists per contest. He is making 41.3% of his shots from the floor and 36.5% from 3-point range, with an average of 1.4 triples.

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