Cardinals vs Rockies Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 11:12 p.m.

The MLB's Sunday slate includes the St. Louis Cardinals taking on the Colorado Rockies.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cardinals vs Rockies Game Info

• St. Louis Cardinals (71-71) vs. Colorado Rockies (54-87)
• Date: Sunday, September 6, 2026
• Time: 3:10 p.m. ET
• Venue: Coors Field -- Denver, Colorado
• Coverage: Rockies.TV and Cardinals.TV

Cardinals vs Rockies Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-120) | COL: (+102)
• Spread: STL: -1.5 (+122) | COL: +1.5 (-146)
• Total: 10.5 -- Over: (-118) | Under: (-104)

Cardinals vs Rockies Probable Starting Pitchers

Probable Pitchers: Kyle Leahy (Cardinals) - 10-4, 3.13 ERA vs Tanner Gordon (Rockies) - 1-4, 5.18 ERA

The Cardinals will give the nod to Kyle Leahy (10-4, 3.13 ERA), who is eyeing win No. 11 on the season, and the Rockies will counter with Tanner Gordon (1-4, 5.18 ERA). When Leahy starts, his team is 11-13-0 against the spread this season. Leahy's team is 4-5 this season when he starts and they are the moneyline favorite. The Rockies have a 4-4-0 ATS record in Gordon's eight starts that had a set spread. The Rockies have a 3-5 record in Gordon's eight starts this season when they were the moneyline underdog.

Cardinals vs Rockies Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (59.9%)

Cardinals vs Rockies Moneyline

• Looking at the moneyline for Cardinals-Rockies, St. Louis is the favorite at -120, and Colorado is +102 playing at home.

Cardinals vs Rockies Spread

• The Rockies are at +1.5 on the runline against the Cardinals. The Rockies are -146 to cover the spread, and the Cardinals are +122.

Cardinals vs Rockies Over/Under

• The Cardinals-Rockies game on Sept. 6 has been given an over/under of 10.5 runs. The over is set at -118 and the under at -104.

Bet on St. Louis Cardinals vs. Colorado Rockies on FanDuel today!

Cardinals vs Rockies Betting Trends

• The Cardinals have been chosen as favorites in 43 games this year and have walked away with the win 24 times (55.8%) in those games.
• This season St. Louis has come away with a win 14 times in 24 chances when named as a favorite of at least -120 on the moneyline.
• The Cardinals and their opponents have gone over in 61 of their 138 games with a total set by sportsbooks this season.
• The Cardinals have an against the spread record of 75-63-0 in 138 games with a line this season.
• The Rockies have gone 51-83 in games they were the underdog on the moneyline (winning 38.1% of those games).
• Colorado is 47-81 (winning just 36.7% of its games) when it has played as a moneyline underdog of +102 or longer.
• The Rockies have had an over/under set by bookmakers 138 times, and have combined with opponents to go over the total in 65 of those games (65-70-3).
• The Rockies have gone 75-63-0 ATS this season.

Cardinals Player Leaders

• Alec Burleson is batting .281 with 33 doubles, a triple, 21 home runs and 48 walks. He has an on-base percentage of .345 while slugging .464.
• Among the qualified hitters in MLB, his batting average ranks 22nd, his on-base percentage ranks 46th, and he is 36th in slugging.
• Jordan Walker has 156 hits to go with a slugging percentage of .504, both of which are tops among St. Louis hitters this season. He's batting .289 with an on-base percentage of .343.
• He is 12th in batting average, 49th in on-base percentage and 14th in slugging in the majors.
• Walker brings a four-game streak with at least one hit into this matchup. In his last five games he is hitting .318 with three doubles, a home run and three RBIs.
• Ivan Herrera leads St. Louis in OBP (.359) this season, fueled by 131 hits.
• Herrera heads into this game with two games in a row with at least one hit. During his last five outings he is batting .348 with a double, a home run, two walks and six RBIs.
• Nathan Church is batting .242 with a .284 OBP and 47 RBI for St. Louis this season.
• Church heads into this game on a four-game hitting streak. During his last five outings he is hitting .250 with an RBI.

Rockies Player Leaders

• TJ Rumfield has a team-best OBP (.388) and slugging percentage (.455). He's batting .295.
• He is ninth in batting average, fifth in on-base percentage and 44th in slugging percentage among all qualified hitters in MLB.
• Rumfield enters this game on a nine-game hitting streak. During his last 10 outings he is hitting .406 with a double, a triple, two home runs, 14 walks and five RBIs.
• Jake McCarthy is batting .289 with 29 doubles, eight triples, 14 home runs and 26 walks. He's slugging .477 with an on-base percentage of .332.
• His batting average ranks 12th among all qualified players, his on-base percentage ranks 68th, and he is 29th in slugging.
• Hunter Goodman has collected 113 hits, a team-best for the Rockies.
• Willi Castro is batting .260 with 20 doubles, a triple, 15 home runs and 41 walks.

Cardinals vs Rockies Head to Head

• 9/4/2026: 7-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/9/2026: 7-4 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +146)
• 8/8/2026: 8-6 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +142)
• 8/7/2026: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -164, Underdog Moneyline: +150)
• 8/13/2025: 6-5 COL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 8/11/2025: 3-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 7/23/2025: 6-0 COL (Favorite: Cardinals, Spread: -1.5, Total: 11, Favorite Moneyline: -186, Underdog Moneyline: +156)
• 7/22/2025: 8-4 COL (Favorite: Cardinals, Spread: -1.5, Total: 12, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 7/21/2025: 6-2 STL (Favorite: Cardinals, Spread: -1.5, Total: 11.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 9/26/2024: 10-8 COL (Favorite: Cardinals, Spread: -1.5, Total: 10.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!