Cardinals vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for July 24

Odds updated as of 5:13 a.m.

The St. Louis Cardinals will face the Cincinnati Reds in MLB action on Friday.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Cardinals vs Reds Game Info

• St. Louis Cardinals (52-50) vs. Cincinnati Reds (47-54)
• Date: Friday, July 24, 2026
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Reds.TV

Cardinals vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-164) | CIN: (+138)
• Spread: STL: -1.5 (+128) | CIN: +1.5 (-154)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Cardinals vs Reds Probable Starting Pitchers

Probable Pitchers: Dustin May (Cardinals) - 5-7, 4.78 ERA vs Rhett Lowder (Reds) - 3-7, 5.75 ERA

The probable starters are Dustin May (5-7) for the Cardinals and Rhett Lowder (3-7) for the Reds. May and his team are 11-8-0 ATS this season when he starts. May's team has been victorious in 80% of the games he's started as the moneyline favorite with a record of 4-1. The Reds have a 6-8-0 ATS record in Lowder's 14 starts that had a set spread. The Reds have been the underdog on the moneyline in 12 of Lowder's starts this season, and they went 5-7 in those matchups.

Cardinals vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (61.2%)

Cardinals vs Reds Moneyline

• The moneyline numbers for Cardinals vs. Reds reveal St. Louis as the favorite (-164) and Cincinnati as the underdog (+138) on the road.

Cardinals vs Reds Spread

• The Cardinals are hosting the Reds and are favored by 1.5 runs on the spread. The Cardinals are +128 to cover the runline, with the Reds being -154.

Cardinals vs Reds Over/Under

• A combined run total of 8.5 has been set for Cardinals-Reds on July 24, with the over at -110 and the under at -110.

Bet on St. Louis Cardinals vs. Cincinnati Reds on FanDuel today!

Cardinals vs Reds Betting Trends

• The Cardinals have won in 16, or 57.1%, of the 28 contests they have been named as odds-on favorites in this year.
• St. Louis has played as a favorite of -164 or more just one time this year and came away with a win in that game.
• The Cardinals and their opponents have gone over the total this season in 41 of their 100 opportunities.
• In 100 games with a line this season, the Cardinals have a mark of 56-44-0 against the spread.
• The Reds have compiled a 31-36 record in games they were listed as the moneyline underdog (winning 46.3% of those games).
• Cincinnati has a record of 4-7 when it has played as a moneyline underdog with odds of +138 or longer (36.4%).
• The Reds have had an over/under set by bookmakers 99 times, and have combined with opponents to go over the total in 55 of those games (55-43-1).
• The Reds have a 54-45-0 record against the spread this season (covering 54.5% of the time).

Cardinals Player Leaders

• Jordan Walker leads St. Louis in slugging percentage (.519) and total hits (112) this season. He's batting .291 with an on-base percentage of .352.
• Among qualified batters in the majors, he ranks 15th in batting average, 46th in on-base percentage, and 15th in slugging.
• Alec Burleson is batting .284 with 25 doubles, a triple, 15 home runs and 34 walks. He's slugging .469 with an on-base percentage of .345.
• He ranks 24th in batting average, 59th in on-base percentage and 39th in slugging among qualified hitters.
• JJ Wetherholt is batting .259 with a .403 slugging percentage and 40 RBI this year.
• Wetherholt brings a two-game hitting streak into this game. In his last five games he is batting .182 with a home run, a walk and three RBIs.
• Ivan Herrera leads St. Louis in OBP (.366) this season, fueled by 90 hits.

Reds Player Leaders

• Sal Stewart has put up a team-high .472 slugging percentage. He's batting .249 with an on-base percentage of .327.
• Including all qualifying players, he is 86th in batting average, while his on-base percentage is 82nd and he is 37th in slugging.
• Elly De La Cruz's 90 hits and .351 OBP both lead his team. He has a batting average of .276 while slugging .503.
• Including all qualified players, he ranks 40th in batting average, 48th in on-base percentage and 21st in slugging percentage.
• JJ Bleday is hitting .237 with 11 doubles, a triple, 17 home runs and 41 walks.
• Spencer Steer is hitting .242 with 14 doubles, 16 home runs and 34 walks.

Cardinals vs Reds Head to Head

• 6/7/2026: 5-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 6/6/2026: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/5/2026: 10-3 STL (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/23/2026: 7-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/23/2026: 8-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/17/2025: 6-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/16/2025: 3-0 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2025: 11-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/31/2025: 7-4 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/30/2025: 4-2 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!