Cardinals vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 20

Odds updated as of 7:15 p.m.

In MLB action on Friday, the Cleveland Guardians take on the St. Louis Cardinals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this game.

Guardians vs Cardinals Game Info

• Cleveland Guardians (89-65) vs. St. Louis Cardinals (77-76)
• Date: Friday, September 20, 2024
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: BSMW

Guardians vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-136) | STL: (+116)
• Spread: CLE: -1.5 (+128) | STL: +1.5 (-154)
• Total: 8 -- Over: (-105) | Under: (-115)

Guardians vs Cardinals Probable Starting Pitchers

Probable Pitchers: Ben Lively (Guardians) - 12-9, 3.87 ERA vs Kyle Gibson (Cardinals) - 8-7, 4.11 ERA

The Guardians will give the ball to Ben Lively (12-9, 3.87 ERA), who is eyeing win No. 13 on the season, and the Cardinals will counter with Kyle Gibson (8-7, 4.11 ERA). Lively's team is 16-10-0 against the spread this season in his starts. Lively's team has been victorious in 87.5% of the games he's started as the moneyline favorite with a record of 14-2. The Cardinals have a 12-14-0 ATS record in Gibson's 26 starts that had a set spread. The Cardinals have been the underdog on the moneyline in 14 of Gibson's starts this season, and they went 8-6 in those matchups.

Guardians vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (56%)

Guardians vs Cardinals Moneyline

• St. Louis is the underdog, +116 on the moneyline, while Cleveland is a -136 favorite despite being on the road.

Guardians vs Cardinals Spread

• The Guardians are 1.5-run road favorites on the runline against the Cardinals. The Guardians are +128 to cover, and the Cardinals are -154.

Guardians vs Cardinals Over/Under

• Guardians versus Cardinals, on Sept. 20, has an over/under of 8, with the over being -105 and the under -115.

Bet on Cleveland Guardians vs. St. Louis Cardinals on FanDuel today!

Guardians vs Cardinals Betting Trends

• The Guardians have come away with 61 wins in the 92 contests they have been listed as the favorites in this season.
• This season Cleveland has come away with a win 29 times in 49 chances when named as a favorite of at least -136 on the moneyline.
• The Guardians and their opponents have hit the over in 69 of their 152 games with a total set by oddsmakers this season.
• The Guardians have an against the spread record of 81-71-0 in 152 games with a line this season.
• The Cardinals have been the moneyline underdog 78 total times this season. They've gone 37-41 in those games.
• St. Louis has a record of 13-20 in games it has played as a moneyline underdog with odds of +116 or longer (39.4%).
• The Cardinals have had an over/under set by oddsmakers 148 times, and have combined with opponents to go over the total in 68 of those games (68-78-2).
• The Cardinals have collected a 71-77-0 record ATS this season (covering 48% of the time).

Guardians Player Leaders

• Jose Ramirez leads Cleveland in slugging percentage (.510) and total hits (161) this season. He's batting .271 with an on-base percentage of .329.
• Among all qualifying hitters in MLB, he is 34th in batting average, 54th in on-base percentage, and 15th in slugging.
• Josh Naylor is hitting .244 with 26 doubles, 31 home runs and 55 walks, while slugging .465 with an on-base percentage of .321.
• Among qualified hitters, his batting average places him 93rd, his on-base percentage 75th, and his slugging percentage 37th.
• Naylor has picked up a hit in two games in a row. In his last five games he is batting .250 with a double, two home runs, a walk and two RBI.
• Andres Gimenez has 142 hits this season and has a slash line of .253/.301/.337.
• Gimenez has picked up a hit in two games in a row. During his last five outings he is hitting .250 with a double, a walk and two RBI.
• Lane Thomas is batting .241 with a .313 OBP and 59 RBI for Cleveland this season.

Cardinals Player Leaders

• Brendan Donovan has an on-base percentage of .342 and a slugging percentage of .414. Both lead the Cardinals. He's batting .277.
• He ranks 30th in batting average, 33rd in on-base percentage and 77th in slugging percentage among all qualified hitters in the big leagues.
• Donovan hopes to build on a four-game hitting streak in this matchup. During his last five outings he is hitting .444 with three doubles, a home run, three walks and five RBI.
• Alec Burleson's 140 hits lead his team. He has a batting average of .269 while slugging .427 with an on-base percentage of .313.
• He is currently 38th in batting average, 97th in on-base percentage and 68th in slugging percentage among all qualified batters.
• Nolan Arenado is batting .268 with 22 doubles, 16 home runs and 44 walks.
• Masyn Winn is hitting .269 with 27 doubles, four triples, 14 home runs and 39 walks.

New to FanDuel Sportsbook? You’ll receive $200 in Bonus Bets guaranteed after your first bet of $5+ is placed! See here for full terms and conditions. Learn about today’s other offers at FanDuel Sportsbook Promos.