Brewers vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for June 22

Odds updated as of 2:12 a.m.

Monday's slate in the MLB includes a matchup between the Milwaukee Brewers and the Cincinnati Reds.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Reds Game Info

• Milwaukee Brewers (46-29) vs. Cincinnati Reds (37-39)
• Date: Monday, June 22, 2026
• Time: 7:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Brewers.TV

Brewers vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-162) | CIN: (+136)
• Spread: MIL: -1.5 (+102) | CIN: +1.5 (-122)
• Total: 9.5 -- Over: (-108) | Under: (-112)

Brewers vs Reds Probable Starting Pitchers

Probable Pitchers: Brandon Woodruff (Brewers) - 2-1, 3.60 ERA vs Brady Singer (Reds) - 3-6, 5.32 ERA

The Brewers will give the nod to Brandon Woodruff (2-1, 3.60 ERA), who is eyeing win No. 3 on the season, and the Reds will counter with Brady Singer (3-6, 5.32 ERA). Woodruff's team is 4-2-0 against the spread in his starts this season. Woodruff's team is 3-1 this season when he starts and they are the moneyline favorite. The Reds have gone 8-5-0 ATS in Singer's 13 starts that had a set spread. The Reds have a 5-6 record in Singer's 11 starts this season when they were the moneyline underdog.

Brewers vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (61.2%)

Brewers vs Reds Moneyline

• Cincinnati is a +136 underdog on the moneyline, while Milwaukee is a -162 favorite on the road.

Brewers vs Reds Spread

• The Reds are +1.5 on the run line against the Brewers. The Reds are -122 to cover, and the Brewers are +102.

Brewers vs Reds Over/Under

• A total of 9.5 runs has been set for the Brewers-Reds contest on June 22, with the over available at -108 and the under at -112.

Bet on Milwaukee Brewers vs. Cincinnati Reds on FanDuel today!

Brewers vs Reds Betting Trends

• The Brewers have been favorites in 50 games this season and have come away with the win 32 times (64%) in those contests.
• Milwaukee has a record of 11-6 when favored by -162 or more this year.
• The Brewers and their opponents have hit the over in 33 of their 75 games with a total set by oddsmakers this season.
• The Brewers have posted a record of 43-32-0 against the spread this season.
• The Reds have won 24 of the 49 games they were the moneyline underdog this season (49%).
• Cincinnati is 2-4 (winning only 33.3% of its games) when it has played as a moneyline underdog of +136 or longer.
• The Reds have played in 74 games with an over/under set, and have combined with opponents to go over the total 44 times (44-29-1).
• The Reds have a 41-33-0 record ATS this season (covering 55.4% of the time).

Brewers Player Leaders

• Brice Turang is hitting .259 with 15 doubles, two triples, 11 home runs and 49 walks. He has an on-base percentage of .371 and a slugging percentage of .452.
• Among qualified hitters, he is 68th in batting average, his on-base percentage ranks 26th, and he is 56th in slugging.
• William Contreras leads Milwaukee in slugging percentage (.417) thanks to 19 extra-base hits. He's batting .299 with an on-base percentage of .358.
• He is 11th in batting average, 44th in on-base percentage and 89th in slugging among qualified hitters.
• Contreras brings a two-game streak with at least one hit into this matchup. During his last five outings he is hitting .438 with a home run, three walks and three RBIs.
• Jake Bauers has 61 hits and an OBP of .373, both of which lead the Brewers this season.
• Sal Frelick is batting .235 with a .306 OBP and 29 RBI for Milwaukee this season.

Reds Player Leaders

• Sal Stewart has a .455 slugging percentage, which paces the Reds. He's batting .252 with an on-base percentage of .344.
• Including all the qualified hitters in the majors, his batting average is 80th, his on-base percentage ranks 60th, and he is 55th in slugging.
• Spencer Steer is hitting .240 with 13 doubles, 12 home runs and 29 walks. He's slugging .430 with an on-base percentage of .322.
• Including all qualifying hitters, he ranks 105th in batting average, 93rd in on-base percentage and 76th in slugging percentage.
• JJ Bleday has 11 doubles, a triple, 13 home runs and 28 walks while batting .254.
• Matt McLain is hitting .204 with 13 doubles, eight home runs and 34 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!