Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 7

Odds updated as of 1:12 p.m.

The Milwaukee Brewers are among the MLB squads in action on Sunday, versus the Pittsburgh Pirates.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info regarding this matchup.

Brewers vs Pirates Game Info

• Milwaukee Brewers (88-55) vs. Pittsburgh Pirates (64-79)
• Date: Sunday, September 7, 2025
• Time: 1:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and FDSWI

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-136) | PIT: (+116)
• Spread: MIL: -1.5 (+122) | PIT: +1.5 (-146)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 4-2, 4.50 ERA vs Bubba Chandler (Pirates) - 2-0, 2.25 ERA

The probable pitchers are Jacob Misiorowski (4-2) for the Brewers and Bubba Chandler (2-0) for the Pirates. Misiorowski and his team are 7-4-0 ATS this season when he starts. When Misiorowski starts a game and his team is the favorite on the moneyline, they have a record of 2-3. Chandler did not pitch as a moneyline underdog a season ago.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (57.3%)

Brewers vs Pirates Moneyline

• Looking at the moneyline for Pirates-Brewers, Pittsburgh is the underdog at +116, and Milwaukee is -136 playing on the road.

Brewers vs Pirates Spread

• The Pirates are at +1.5 on the runline against the Brewers. The Pirates are -146 to cover the spread, and the Brewers are +122.

Brewers vs Pirates Over/Under

• The over/under for the Brewers versus Pirates contest on Sept. 7 has been set at 7.5, with -118 odds on the over and -104 odds on the under.

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Brewers vs Pirates Betting Trends

• The Brewers have been victorious in 52, or 65.8%, of the 79 contests they have been chosen as favorites in this season.
• This season Milwaukee has been victorious 32 times in 44 chances when named as a favorite of at least -136 on the moneyline.
• The Brewers' games have gone over the total in 69 of their 140 opportunities.
• In 140 games with a line this season, the Brewers have a mark of 80-60-0 against the spread.
• The Pirates have won 43.2% of the games this season they were the moneyline underdog (41-54).
• When playing as a moneyline underdog with odds of +116 or longer, Pittsburgh has a record of 24-41 (36.9%).
• The Pirates have had an over/under set by oddsmakers 135 times, and have combined with opponents to go over the total in 53 of those games (53-76-6).
• The Pirates have a 74-61-0 record against the spread this season.

Brewers Player Leaders

• William Contreras is batting .263 with 26 doubles, 17 home runs and 77 walks. He has an on-base percentage of .359 while slugging .411.
• Among all qualifying hitters in MLB, his batting average ranks 64th, his on-base percentage ranks 25th, and he is 94th in slugging.
• Contreras has hit safely in six games in a row. In his last 10 outings he is batting .293 with two doubles, two home runs, three walks and four RBIs.
• Brice Turang leads Milwaukee in slugging percentage (.447) thanks to 44 extra-base hits. He's batting .291 with an on-base percentage of .358.
• Among all qualified hitters, he ranks 14th in batting average, 26th in on-base percentage and 66th in slugging percentage.
• Turang takes a two-game streak with at least one hit into this contest. During his last five outings he is hitting .438 with a double, a triple, a home run, three walks and three RBIs.
• Christian Yelich is batting .268 with a .464 slugging percentage and 92 RBI this year.
• Jackson Chourio leads Milwaukee with 130 hits, batting .275 this season with 54 extra-base hits.

Pirates Player Leaders

• Bryan Reynolds has 129 hits with a .412 slugging percentage, both team-high numbers for the Pirates. He's batting .247 and with an on-base percentage of .316.
• He ranks 99th in batting average, 103rd in on-base percentage and 91st in slugging percentage among all qualifying hitters in the majors.
• Oneil Cruz is batting .203 with 17 doubles, two triples, 19 home runs and 60 walks. He's slugging .388 with an on-base percentage of .305.
• His batting average ranks 151st among all qualified players, his on-base percentage is 123rd, and he is 121st in slugging.
• Andrew McCutchen has racked up an on-base percentage of .339, a team-best for the Pirates.
• Tommy Pham is hitting .261 with 17 doubles, a triple, eight home runs and 39 walks.

Brewers vs Pirates Head to Head

• 9/6/2025: 4-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/5/2025: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/13/2025: 12-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/12/2025: 14-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 8/11/2025: 7-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/25/2025: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/24/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 6/23/2025: 5-4 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 5/25/2025: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/24/2025: 2-1 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)

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