Brewers vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 17

Odds updated as of 8:13 p.m.

In MLB action on Thursday, the Milwaukee Brewers face the Pittsburgh Pirates.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Pirates Game Info

• Milwaukee Brewers (94-57) vs. Pittsburgh Pirates (75-76)
• Date: Thursday, September 17, 2026
• Time: 12:35 p.m. ET
• Venue: PNC Park -- Pittsburgh, Pennsylvania
• Coverage: SportsNet PT and Brewers.TV

Brewers vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-132) | PIT: (+112)
• Spread: MIL: -1.5 (+122) | PIT: +1.5 (-146)
• Total: 8.5 -- Over: (-142) | Under: (+116)

Brewers vs Pirates Probable Starting Pitchers

Probable Pitchers: Kyle Harrison (Brewers) - 10-4, 3.98 ERA vs TBA (Pirates)

The Brewers will look to Kyle Harrison (10-4), while the Pirates' starter has not yet been announced. Harrison and his team are 14-9-0 ATS this season when he starts. Harrison's team has a record of 9-8 this season when he starts and they are the favorite on the moneyline.

Brewers vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (61.2%)

Brewers vs Pirates Moneyline

• Looking at the moneyline for Brewers-Pirates, Milwaukee is the favorite at -132, and Pittsburgh is +112 playing at home.

Brewers vs Pirates Spread

• The Pirates are +1.5 on the run line against the Brewers. The Pirates are -146 to cover, and the Brewers are +122.

Brewers vs Pirates Over/Under

• The over/under for Brewers-Pirates on Sept. 17 is 8.5. The over is -142, and the under is +116.

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Brewers vs Pirates Betting Trends

• The Brewers have come away with 75 wins in the 117 contests they have been listed as the favorites in this season.
• Milwaukee has a record of 55-30 in contests when bookmakers favor them by -132 or more on the moneyline.
• The Brewers and their opponents have gone over in 65 of their 150 games with a total set by sportsbooks this season.
• The Brewers are 79-71-0 against the spread in their 150 games with a line set by sportsbooks this season.
• The Pirates have been the underdog on the moneyline 71 total times this season. They've gone 31-40 in those games.
• Pittsburgh has a 16-23 record (winning 41% of its games) when it has played as a moneyline underdog of +112 or longer.
• The Pirates have played in 149 games with an over/under set, and have combined with their opponents to go over the total 77 times (77-68-4).
• The Pirates have collected a 72-77-0 record against the spread this season (covering 48.3% of the time).

Brewers Player Leaders

• Brice Turang has 33 doubles, three triples, 19 home runs and 87 walks while batting .267. He has an on-base percentage of .368 and a slugging percentage of .444.
• Among all qualifying hitters in baseball, he is 51st in batting average, 18th in on-base percentage, and 51st in slugging.
• William Contreras has hit 17 homers this season while driving in 86 runs. He's batting .272 this season and slugging .420 with an on-base percentage of .342.
• His batting average ranks 38th among qualified players, his on-base percentage 52nd, and his slugging percentage 76th.
• Contreras has picked up at least one hit in five straight games. During his last five outings he is batting .350 with a double, three home runs, four walks and 12 RBIs.
• Jake Bauers has 120 hits and an OBP of .393, both of which lead the Brewers this season.
• Bauers takes a four-game hitting streak into this game. In his last five games he is hitting .250 with two home runs, a walk and five RBIs.
• Jackson Chourio is batting .289 with a .346 OBP and 67 RBI for Milwaukee this season.

Pirates Player Leaders

• Bryan Reynolds has 36 doubles, two triples, 17 home runs and 84 walks while hitting .264. He's slugging .426 with an on-base percentage of .368.
• Including all qualified hitters, he ranks 57th in batting average, while his on-base percentage ranks 18th and he is 69th in slugging.
• Brandon Lowe has racked up 141 hits to pace his team. He has a batting average of .258 while slugging .477 with an on-base percentage of .326.
• Including all qualified hitters, he ranks 66th in batting average, 77th in on-base percentage and 26th in slugging percentage.
• Nick Gonzales has put up a .370 on-base percentage and a .395 slugging percentage, both team-best numbers for the Pirates.
• Ryan O'Hearn is batting .266 with 15 doubles, 18 home runs and 32 walks.

Brewers vs Pirates Head to Head

• 9/15/2026: 5-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 8/6/2026: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: +110)
• 8/5/2026: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +114)
• 8/4/2026: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +132)
• 8/3/2026: 4-3 PIT (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +136)
• 7/12/2026: 14-5 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/11/2026: 3-2 PIT (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/11/2026: 7-6 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/26/2026: 5-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/25/2026: 6-3 PIT (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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