Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for NLDS Game 2 on Oct. 6

Odds updated as of 5:12 a.m.

On Monday in the MLB, the Milwaukee Brewers are playing the Chicago Cubs for Game 2 of the NLDS.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Cubs Game Info

• Milwaukee Brewers (97-65) vs. Chicago Cubs (92-70)
• Date: Monday, October 6, 2025
• Time: 9:08 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: TBS, truTV, and HBO Max

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-120) | CHC: (+102)
• Spread: MIL: -1.5 (+176) | CHC: +1.5 (-215)
• Total: 8 -- Over: (-105) | Under: (-115)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Aaron Ashby (Brewers) - 5-2, 2.16 ERA vs Shota Imanaga (Cubs) - 9-8, 3.73 ERA

The Brewers will give the nod to Aaron Ashby (5-2, 2.16 ERA) versus the Cubs and Shota Imanaga (9-8, 3.73 ERA). Ashby and his team failed to cover the spread in his only opportunity this season as a starter. Ashby's team lost his only start as a favorite this season. When Imanaga starts, the Cubs are 9-15-0 against the spread. The Cubs are 4-4 in Imanaga's eight starts this season that they were the underdog on the moneyline.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (50.2%)

Brewers vs Cubs Moneyline

• Chicago is a +102 underdog on the moneyline, while Milwaukee is a -120 favorite at home.

Brewers vs Cubs Spread

• The Cubs are at +1.5 on the runline against the Brewers. The Cubs are -215 to cover the spread, and the Brewers are +176.

Brewers vs Cubs Over/Under

• Brewers versus Cubs on Oct. 6 has an over/under of 8 runs, with the odds on the over -105 and the under set at -115.

Bet on Milwaukee Brewers vs. Chicago Cubs on FanDuel today!

Brewers vs Cubs Betting Trends

• The Brewers have come away with 61 wins in the 97 contests they have been listed as the favorites in this season.
• This season Milwaukee has come away with a win 52 times in 77 chances when named as a favorite of at least -120 on the moneyline.
• The Brewers and their opponents have hit the over in 80 of their 160 games with a total set by oddsmakers this season.
• The Brewers have posted a record of 88-72-0 against the spread this season.
• The Cubs have put together an 18-27 record in games they were the underdog on the moneyline (winning 40% of those games).
• Chicago has a record of 11-17 when playing as a moneyline underdog with odds of +102 or longer (39.3%).
• The Cubs have played in 161 games with a set over/under, and have combined with their opponents to go over the total 75 times (75-75-11).
• The Cubs have gone 77-84-0 against the spread this season.

Brewers Player Leaders

• Brice Turang leads Milwaukee with an OBP of .359, plus a team-best slugging percentage of .435. He's batting .288 on the season.
• Among all qualified hitters in MLB, his batting average ranks 16th, his on-base percentage ranks 20th, and he is 71st in slugging.
• Turang hopes to build on a five-game hitting streak in this matchup. During his last five outings he is hitting .421 with three doubles, three walks and five RBIs.
• Christian Yelich is batting .264 with 21 doubles, 29 home runs and 64 walks, while slugging .452 with an on-base percentage of .343.
• He ranks 51st in batting average, 49th in on-base percentage and 56th in slugging in the majors.
• William Contreras is batting .260 with a .399 slugging percentage and 76 RBI this year.
• Jackson Chourio has 148 hits, which leads Milwaukee hitters this season, while batting .270 with 60 extra-base hits.
• Chourio has safely hit in three games in a row. During his last five outings he is batting .368 with two doubles, a home run, two walks and four RBIs.

Cubs Player Leaders

• Kyle Tucker has put up an on-base percentage of .377, a team-high for the Cubs. He's batting .266 and slugging .464.
• Including all qualifying hitters in the majors, he is 46th in batting average, seventh in on-base percentage and 44th in slugging percentage.
• Nico Hoerner's .394 slugging percentage leads his team. He has a batting average of .297 with an on-base percentage of .345.
• He is currently eighth in batting average, 46th in on-base percentage and 110th in slugging percentage among all qualified hitters.
• Pete Crow-Armstrong has 37 doubles, four triples, 31 home runs and 29 walks while hitting .247.
• Seiya Suzuki is hitting .245 with 31 doubles, three triples, 32 home runs and 71 walks.

Brewers vs Cubs Head to Head

• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2025: 4-1 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/19/2025: 6-4 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/18/2025: 7-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/30/2025: 10-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/29/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 7/28/2025: 8-4 MIL (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/19/2025: 8-7 MIL (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +108)

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