Brewers vs Cubs Prediction, Odds, Moneyline, Spread & Over/Under for June 26

Odds updated as of 4:12 a.m.

The MLB's Friday schedule includes the Milwaukee Brewers facing the Chicago Cubs.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Cubs Game Info

• Milwaukee Brewers (49-29) vs. Chicago Cubs (44-37)
• Date: Friday, June 26, 2026
• Time: 7:45 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: Apple TV+

Brewers vs Cubs Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-270) | CHC: (+220)
• Spread: MIL: -1.5 (-125) | CHC: +1.5 (+104)
• Total: 7.5 -- Over: (-108) | Under: (-112)

Brewers vs Cubs Probable Starting Pitchers

Probable Pitchers: Jacob Misiorowski (Brewers) - 8-3, 1.45 ERA vs Colin Rea (Cubs) - 5-5, 4.99 ERA

The Brewers will give the nod to Jacob Misiorowski (8-3, 1.45 ERA), who is eyeing win No. 9 on the season, and the Cubs will turn to Colin Rea (5-5, 4.99 ERA). Misiorowski and his team are 10-5-0 ATS this season when he starts. Misiorowski's team has been victorious in 66.7% of the games he's started as the moneyline favorite with a record of 8-4. The Cubs have a 3-9-0 record against the spread in Rea's starts. The Cubs are 2-2 in Rea's four starts this season that they were the moneyline underdog.

Brewers vs Cubs Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (61.5%)

Brewers vs Cubs Moneyline

• Chicago is a +220 underdog on the moneyline, while Milwaukee is a -270 favorite at home.

Brewers vs Cubs Spread

• The Cubs are +1.5 on the run line against the Brewers. The Cubs are +104 to cover, and the Brewers are -125.

Brewers vs Cubs Over/Under

• The over/under for Brewers-Cubs on June 26 is 7.5. The over is -108, and the under is -112.

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Brewers vs Cubs Betting Trends

• The Brewers have been favorites in 52 games this season and have come away with the win 34 times (65.4%) in those contests.
• Milwaukee has played as a favorite of -270 or more just one time this year and came away with a win in that game.
• The Brewers and their opponents have gone over the total this season in 34 of their 78 opportunities.
• The Brewers have an against the spread record of 44-34-0 in 78 games with a line this season.
• The Cubs have won 12 of the 23 games they were listed as the moneyline underdog this season (52.2%).
• Chicago has never played a game this season with moneyline odds of +220 or longer.
• The Cubs have played in 79 games with an over/under set, and have combined with opponents to go over the total 42 times (42-37-0).
• The Cubs are 32-47-0 ATS this season.

Brewers Player Leaders

• Brice Turang has 16 doubles, three triples, 11 home runs and 49 walks while hitting .265. He has an on-base percentage of .371 and a slugging percentage of .459.
• Among qualified hitters in MLB, he ranks 57th in batting average, 25th in on-base percentage, and 55th in slugging.
• Turang hopes to build on a four-game hitting streak in this matchup. In his last five games he is batting .273 with a double, a triple and an RBI.
• William Contreras leads Milwaukee in slugging percentage (.427) thanks to 20 extra-base hits. He's batting .302 with an on-base percentage of .365.
• Among qualifying hitters, his batting average ranks him ninth, his on-base percentage 33rd, and his slugging percentage 78th.
• Contreras enters this game looking to extend his two-game hit streak. During his last five outings he is batting .526 with two home runs, three walks and five RBIs.
• Jake Bauers has 64 hits and an OBP of .377, both of which lead the Brewers this season.
• Bauers has logged a hit or more in two straight games. In his last five games he is hitting .294 with a triple, a home run, three walks and two RBIs.
• Sal Frelick is batting .232 with a .302 OBP and 29 RBI for Milwaukee this season.

Cubs Player Leaders

• Pete Crow-Armstrong has racked up 88 hits with a .521 slugging percentage, both team-best stats for the Cubs. He's batting .287 and with an on-base percentage of .367.
• Including all the qualifying players in the big leagues, his batting average ranks 22nd, his on-base percentage is 32nd, and he is 15th in slugging.
• Crow-Armstrong takes a 14-game hitting streak into this matchup. In his last 10 outings he is batting .439 with two doubles, a triple, five home runs, eight walks and 12 RBIs.
• Nico Hoerner is hitting .239 with 21 doubles, four home runs and 34 walks. He's slugging .343 with an on-base percentage of .317.
• He is 107th in batting average, 105th in on-base percentage and 136th in slugging percentage in the majors.
• Ian Happ has 15 doubles, two triples, 16 home runs and 44 walks while hitting .229.
• Michael Busch's .370 OBP leads his team.

Brewers vs Cubs Head to Head

• 5/20/2026: 5-0 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 5/19/2026: 5-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/18/2026: 9-3 MIL (Favorite: Cubs, Spread: -1.5, Total: 10.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 10/11/2025: 3-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 10/9/2025: 6-0 CHC (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 10/8/2025: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 10/6/2025: 7-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 10/4/2025: 9-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/21/2025: 4-1 MIL (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2025: 4-3 CHC (Favorite: Brewers, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)

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