Brewers vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for May 4

Odds updated as of 2:12 a.m.

On Monday in MLB, the Milwaukee Brewers are playing the St. Louis Cardinals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Brewers vs Cardinals Game Info

• Milwaukee Brewers (18-15) vs. St. Louis Cardinals (20-14)
• Date: Monday, May 4, 2026
• Time: 7:45 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Fox Sports 1, Cardinals.TV, and Brewers.TV

Brewers vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-110) | STL: (-106)
• Spread: MIL: -1.5 (+146) | STL: +1.5 (-176)
• Total: 8.5 -- Over: (+100) | Under: (-122)

Brewers vs Cardinals Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 2-1, 2.57 ERA vs Kyle Leahy (Cardinals) - 3-3, 5.52 ERA

The Brewers will call on Chad Patrick (2-1) against the Cardinals and Kyle Leahy (3-3). Patrick and his team have covered in each of his four starts with a spread this season. Patrick has started three games with his team as the moneyline favorite and won each of them. The Cardinals are 3-3-0 ATS in Leahy's six starts with a set spread. The Cardinals are 3-3 in Leahy's six starts this season that they were the underdog on the moneyline.

Brewers vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (55.8%)

Brewers vs Cardinals Moneyline

• Looking at the moneyline for Brewers-Cardinals, Milwaukee is the favorite at -110, and St. Louis is -106 playing at home.

Brewers vs Cardinals Spread

• The Cardinals are hosting the Brewers, and are +1.5 on the runline. The Cardinals are +146 to cover the spread, and the Brewers are -176.

Brewers vs Cardinals Over/Under

• A total of 8.5 runs has been set for the Brewers-Cardinals contest on May 4, with the over available at +100 and the under at -122.

Bet on Milwaukee Brewers vs. St. Louis Cardinals on FanDuel today!

Brewers vs Cardinals Betting Trends

• The Brewers have been chosen as favorites in 21 games this year and have walked away with the win 13 times (61.9%) in those games.
• This year Milwaukee has won 13 of 21 games when listed as at least -110 on the moneyline.
• Contests with the Brewers have gone over the total set by bookmakers in 17 of 33 chances this season.
• In 33 games with a line this season, the Brewers have a mark of 20-13-0 against the spread.
• The Cardinals have won 18 of the 31 games they were the underdog on the moneyline this season (58.1%).
• When playing as a moneyline underdog with odds of -106 or longer, St. Louis has an 18-13 record (winning 58.1% of its games).
• The Cardinals have played in 34 games with a set over/under, and have combined with their opponents to go over the total 18 times (18-15-1).
• The Cardinals are 21-13-0 ATS this season.

Brewers Player Leaders

• Brice Turang leads Milwaukee in OBP (.428) and total hits (32) this season. He's batting .291 batting average while slugging .491.
• Among qualified hitters in the majors, he ranks 34th in batting average, fourth in on-base percentage, and 37th in slugging.
• Turang hopes to build on a five-game hitting streak in this matchup. In his last five games he is hitting .471 with three doubles, six walks and two RBIs.
• William Contreras leads Milwaukee in slugging percentage (.419) thanks to 10 extra-base hits. He's batting .290 with an on-base percentage of .362.
• He ranks 36th in batting average, 47th in on-base percentage and 74th in slugging among qualified hitters.
• Jake Bauers has collected 27 base hits, an OBP of .317 and a slugging percentage of .423 this season.
• Sal Frelick has been key for Milwaukee with 21 hits, an OBP of .305 plus a slugging percentage of .317.

Cardinals Player Leaders

• Jordan Walker has racked up 39 hits with a .591 slugging percentage, both team-high marks for the Cardinals. He's batting .307 and with an on-base percentage of .373.
• Including all the qualifying hitters in the big leagues, his batting average is 24th, his on-base percentage is 40th, and he is seventh in slugging.
• Alec Burleson is hitting .279 with nine doubles, five home runs and 17 walks. He's slugging .465 with an on-base percentage of .361.
• He is currently 43rd in batting average, 51st in on-base percentage and 49th in slugging percentage among all qualifying hitters.
• JJ Wetherholt is batting .238 with five doubles, seven home runs and 17 walks.
• Ivan Herrera has a .417 OBP to lead his team.

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