Blue Jays vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 3

Odds updated as of 6:12 p.m.

Wednesday's slate in the MLB includes a matchup between the Toronto Blue Jays and the Cincinnati Reds.

We've got you covered, in terms of the most important information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Blue Jays vs Reds Game Info

• Toronto Blue Jays (80-59) vs. Cincinnati Reds (70-69)
• Date: Wednesday, September 3, 2025
• Time: 6:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and SNET

Blue Jays vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-154) | CIN: (+130)
• Spread: TOR: -1.5 (+108) | CIN: +1.5 (-130)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Blue Jays vs Reds Probable Starting Pitchers

Probable Pitchers: Shane Bieber (Blue Jays) - 1-1, 2.38 ERA vs Zack Littell (Reds) - 9-8, 3.63 ERA

This contest's pitching matchup is set, as the Blue Jays will send Shane Bieber (1-1) to the mound, while Zack Littell (9-8) will take the ball for the Reds. Bieber has a record of 1-1-0 ATS in two starts with a spread this season. Bieber's team is 1-1 this season when he starts and they're favored on the moneyline. The Reds have a 13-14-0 record against the spread in Littell's starts. The Reds are 8-8 in Littell's 16 starts this season that they were the underdog on the moneyline.

Blue Jays vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Blue Jays win (52%)

Blue Jays vs Reds Moneyline

• Cincinnati is a +130 underdog on the moneyline, while Toronto is a -154 favorite on the road.

Blue Jays vs Reds Spread

• The Blue Jays are at the Reds and are favored by 1.5 runs on the spread. The Blue Jays are +108 to cover the runline, with the Reds being -130.

Blue Jays vs Reds Over/Under

• A combined run total of 8.5 has been set for Blue Jays-Reds on Sept. 3, with the over at -124 and the under at +102.

Bet on Toronto Blue Jays vs. Cincinnati Reds on FanDuel today!

Blue Jays vs Reds Betting Trends

• The Blue Jays have won in 37, or 56.9%, of the 65 contests they have been named as odds-on favorites in this year.
• Toronto has a record of 20-8 when favored by -154 or more this year.
• The Blue Jays and their opponents have gone over in 78 of their 138 games with a total set by sportsbooks this season.
• The Blue Jays have posted a record of 81-57-0 against the spread this season.
• The Reds are 35-38 in games they were listed as the moneyline underdog (winning 47.9% of those games).
• Cincinnati has a 13-14 record (winning 48.1% of its games) when playing as a moneyline underdog of +130 or longer.
• The Reds have played in 132 games with an over/under set, and have combined with opponents to go over the total 53 times (53-73-6).
• The Reds have covered 51.5% of their games this season, going 68-64-0 ATS.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. is hitting .291 with 30 doubles, 21 home runs and 74 walks. He has an on-base percentage of .387 while slugging .478.
• He is 14th in batting average, seventh in on-base percentage, and 36th in slugging among qualified batters in baseball.
• Guerrero has recorded at least one hit in three games in a row. During his last five outings he is batting .263 with two walks and three RBIs.
• Bo Bichette has hit 18 homers this season while driving in 91 runs. He's batting .310 this season and slugging .482 with an on-base percentage of .354.
• Among all qualifying hitters, he is third in batting average, 35th in on-base percentage and 34th in slugging percentage.
• Bichette has picked up a hit in two games in a row. In his last five games he is hitting .400 with two doubles, two home runs, two walks and five RBIs.
• George Springer leads Toronto with 124 hits and an OBP of .396 this season.
• Springer brings a three-game hitting streak into this game. During his last five outings he is hitting .353 with a double, two home runs, three walks and four RBIs.
• Alejandro Kirk is batting .297 with a .362 OBP and 64 RBI for Toronto this season.
• Kirk has hit safely in two straight games. During his last five outings he is hitting .313 with two doubles, two walks and four RBIs.

Reds Player Leaders

• Elly De La Cruz has 148 hits with a .453 slugging percentage, both team-high marks for the Reds. He's batting .272 and with an on-base percentage of .341.
• Including all qualifying hitters in the majors, he is 39th in batting average, 53rd in on-base percentage and 58th in slugging percentage.
• De La Cruz hopes to build on a seven-game hitting streak in this matchup. During his last 10 outings he is batting .244 with three doubles, two triples, a walk and an RBI.
• TJ Friedl's .368 on-base percentage leads his team. He has a batting average of .269 while slugging .382.
• Including all qualifying hitters, his batting average places him 47th, his on-base percentage ranks 16th, and he is 129th in slugging.
• Spencer Steer has 19 doubles, two triples, 17 home runs and 42 walks while batting .235.
• Austin Hays is hitting .263 with 15 doubles, five triples, 13 home runs and 27 walks.

Blue Jays vs Reds Head to Head

• 9/2/2025: 12-9 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/1/2025: 5-4 CIN (Favorite: Reds, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/21/2024: 11-7 CIN (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/20/2024: 10-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/19/2024: 6-3 CIN (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/20/2023: 10-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/19/2023: 4-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 8/18/2023: 1-0 CIN (Favorite: Blue Jays, Spread: -1.5, Total: 10, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/22/2022: 3-2 CIN (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/21/2022: 3-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)

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