Blue Jays vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 28

Odds updated as of 7:11 p.m.

The Toronto Blue Jays are among the MLB squads busy on Tuesday, up against the Boston Red Sox.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's what you need to know.

Blue Jays vs Red Sox Game Info

• Toronto Blue Jays (12-16) vs. Boston Red Sox (12-17)
• Date: Tuesday, April 28, 2026
• Time: 7:07 p.m. ET
• Venue: Rogers Centre -- Toronto, Ontario
• Coverage: SN1 and NESN+

Blue Jays vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-116) | BOS: (-102)
• Spread: TOR: +1.5 (-205) | BOS: -1.5 (+168)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Blue Jays vs Red Sox Probable Starting Pitchers

Probable Pitchers: Trey Yesavage (Blue Jays) - 0-0, 0.00 ERA vs Payton Tolle (Red Sox) - 0-0, 1.50 ERA

This contest's pitching matchup is set, as the Blue Jays will send Trey Yesavage to the mound, while Payton Tolle will get the nod for the Red Sox. Yesavage and his team were 6-2-0 ATS in his eight appearances with a spread last season. Yesavage and his team had a 4-1 record when he pitched as a favorite last season. Tolle has started just one game with a set spread, which the Red Sox failed to cover. The Red Sox were named the moneyline underdog for one Tolle start this season -- they lost.

Blue Jays vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Blue Jays win (50.4%)

Blue Jays vs Red Sox Moneyline

• Looking at the moneyline for Blue Jays-Red Sox, Toronto is the favorite at -116, and Boston is -102 playing on the road.

Blue Jays vs Red Sox Spread

• The Red Sox are 1.5-run favorites against the spread for this matchup with the Blue Jays. The Red Sox are +168 to cover, while the Blue Jays are -205 to cover as a 1.5-run underdog on the runline.

Blue Jays vs Red Sox Over/Under

• The over/under for Blue Jays-Red Sox on April 28 is 7.5. The over is -115, and the under is -105.

Bet on Toronto Blue Jays vs. Boston Red Sox on FanDuel today!

Blue Jays vs Red Sox Betting Trends

• The Blue Jays have won in nine, or 50%, of the 18 contests they have been named as odds-on favorites in this year.
• Toronto has a record of 9-9 in contests when oddsmakers favor them by -116 or more on the moneyline.
• The Blue Jays and their opponents have gone over in 14 of their 28 games with a total set by sportsbooks this season.
• The Blue Jays have an against the spread record of 10-18-0 in 28 games with a line this season.
• The Red Sox have won 33.3% of the games this season they were the underdog on the moneyline (3-6).
• When playing as a moneyline underdog with odds of -102 or longer, Boston has a record of 3-6 (33.3%).
• The Red Sox have combined with opponents to hit the over on the total 15 times this season for a 15-14-0 record against the over/under.
• The Red Sox are 10-19-0 ATS this season.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. has 34 hits this season and a team-best OBP of .415. He has a .330 batting average and a slugging percentage of .447.
• Among all qualifying hitters in the majors, he ranks third in batting average, ninth in on-base percentage, and 63rd in slugging.
• Andres Gimenez leads Toronto with 27 hits. He is batting .287 this season and has 10 extra-base hits. He's also slugging .468 with an on-base percentage of .313.
• He is 33rd in batting average, 119th in on-base percentage and 48th in slugging in the majors.
• Gimenez brings a three-game streak with at least one hit into this matchup. During his last five outings he is batting .353 with three doubles and four RBIs.
• Ernie Clement leads Toronto in slugging percentage (.422) powered by 13 extra-base hits.
• Jesus Sanchez has been key for Toronto with 22 hits, an OBP of .315 plus a slugging percentage of .463.
• Sanchez has hit safely in two straight games. In his last five games he is hitting .286 with a double, two home runs and four RBIs.

Red Sox Player Leaders

• Wilyer Abreu has accumulated a team-high slugging percentage (.491) and paces the Red Sox in hits (33). He's batting .306 and with an on-base percentage of .364.
• Including all qualifying hitters, he ranks 22nd in batting average, while his on-base percentage is 37th and he is 32nd in slugging.
• Abreu brings a six-game hitting streak into this matchup. In his last 10 games he is batting .289 with two doubles, a home run, five walks and three RBIs.
• Willson Contreras paces his team with a .375 on-base percentage. He has a batting average of .253 while slugging .455.
• Including all qualifying hitters, he is 75th in batting average, 24th in on-base percentage and 58th in slugging percentage.
• Caleb Durbin is hitting .174 with six doubles, a home run and 10 walks.
• Ceddanne Rafaela has four doubles, two triples, a home run and six walks while batting .275.

Blue Jays vs Red Sox Head to Head

• 4/27/2026: 5-0 BOS (Favorite: Blue Jays, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/25/2025: 6-1 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/24/2025: 7-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/23/2025: 4-1 BOS (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/29/2025: 5-3 TOR (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/28/2025: 15-1 BOS (Favorite: Blue Jays, Spread: -1.5, Total: 9, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/27/2025: 9-0 TOR (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/1/2025: 4-2 TOR (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/30/2025: 7-6 TOR (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/29/2025: 10-2 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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