Best College Football Games Week 2: Predictions, Odds, Picks, Best Bets

The Week 2 college football slate includes 24 games with a ranked team on the field. Among those contests is the No. 1 Ohio State Buckeyes playing the No. 4 Texas Longhorns.

With Week 2 in college football upon us, stay on top of the most current betting odds with our preview below.

For additional insights, check out the latest college football betting picks from FanDuel Research's staff of writers.

Miami (FL) vs. Florida A&M

• Matchup: Florida A&M Rattlers at No. 7 Miami Hurricanes
• Projected Favorite: Miami (FL)
• Spread: Miami (FL) (-59.5)
• Total: 66.5
• Time: 8 p.m. ET
• Date: Sept. 10
• TV Channel: ACC Network

Bet on Miami (FL) vs. Florida A&M with FanDuel Sportsbook.

Louisville vs. Villanova

• Matchup: Villanova Wildcats at No. 24 Louisville Cardinals
• Projected Favorite: Louisville
• Spread: Louisville (-36.5)
• Total: 56.5
• Time: 7 p.m. ET
• Date: Sept. 11
• TV Channel: ACC Network

Bet on Louisville vs. Villanova with FanDuel Sportsbook.

Virginia vs. Norfolk State

• Matchup: Norfolk State Spartans at No. 25 Virginia Cavaliers
• Projected Favorite: Virginia
• Spread: Virginia (-45.5)
• Total: 54.5
• Time: 7 p.m. ET
• Date: Sept. 11
• TV Channel: ACC Network Extra

Bet on Virginia vs. Norfolk State with FanDuel Sportsbook.

Kansas vs. Missouri

• Matchup: No. 23 Missouri Tigers at Kansas Jayhawks
• Projected Favorite: Missouri (67.01% win probability)
• Spread: Missouri (-5.5)
• Total: 51.5
• Time: 8 p.m. ET
• Date: Sept. 11
• TV Channel: FOX

Bet on Kansas vs. Missouri with FanDuel Sportsbook.

Temple vs. Penn State

• Matchup: No. 16 Penn State Nittany Lions at Temple Owls
• Projected Favorite: Penn State (93.33% win probability)
• Spread: Penn State (-23.5)
• Total: 50.5
• Time: 12 p.m. ET
• Date: Sept. 12
• TV Channel: ESPN2

Bet on Temple vs. Penn State with FanDuel Sportsbook.

Oklahoma State vs. Oregon

• Matchup: No. 6 Oregon Ducks at Oklahoma State Cowboys
• Projected Favorite: Oregon (98.50% win probability)
• Spread: Oregon (-23.5)
• Total: 55.5
• Time: 12 p.m. ET
• Date: Sept. 12
• TV Channel: ESPN

Bet on Oklahoma State vs. Oregon with FanDuel Sportsbook.

Texas A&M vs. Arizona State

• Matchup: Arizona State Sun Devils at No. 10 Texas A&M Aggies
• Projected Favorite: Texas A&M (87.97% win probability)
• Spread: Texas A&M (-14.5)
• Total: 50.5
• Time: 12 p.m. ET
• Date: Sept. 12
• TV Channel: ABC

Bet on Texas A&M vs. Arizona State with FanDuel Sportsbook.

Indiana vs. Howard

• Matchup: Howard Bison at No. 5 Indiana Hoosiers
• Projected Favorite: Indiana
• Spread: Indiana (-56.5)
• Total: 65.5
• Time: 12 p.m. ET
• Date: Sept. 12
• TV Channel: BTN

Bet on Indiana vs. Howard with FanDuel Sportsbook.

Michigan vs. Oklahoma

• Matchup: No. 11 Oklahoma Sooners at Michigan Wolverines
• Projected Favorite: Oklahoma (50.78% win probability)
• Spread: Oklahoma (-4.5)
• Total: 43.5
• Time: 12 p.m. ET
• Date: Sept. 12
• TV Channel: FOX

Bet on Michigan vs. Oklahoma with FanDuel Sportsbook.

Georgia vs. Western Kentucky

• Matchup: Western Kentucky Hilltoppers at No. 2 Georgia Bulldogs
• Projected Favorite: Georgia (96.89% win probability)
• Spread: Georgia (-40.5)
• Total: 55.5
• Time: 12:45 p.m. ET
• Date: Sept. 12
• TV Channel: SEC Network

Bet on Georgia vs. Western Kentucky with FanDuel Sportsbook.

Notre Dame vs. Rice

• Matchup: Rice Owls at No. 3 Notre Dame Fighting Irish
• Projected Favorite: Notre Dame (99.32% win probability)
• Spread: Notre Dame (-44.5)
• Total: 54.5
• Time: 3:30 p.m. ET
• Date: Sept. 12
• TV Channel: NBC/Peacock

Bet on Notre Dame vs. Rice with FanDuel Sportsbook.

Kentucky vs. Alabama

• Matchup: No. 12 Alabama Crimson Tide at Kentucky Wildcats
• Projected Favorite: Alabama (74.83% win probability)
• Spread: Alabama (-10.5)
• Total: 48.5
• Time: 3:30 p.m. ET
• Date: Sept. 12
• TV Channel: ABC

Bet on Kentucky vs. Alabama with FanDuel Sportsbook.

BYU vs. Arizona

• Matchup: Arizona Wildcats at No. 15 BYU Cougars
• Projected Favorite: BYU (76.44% win probability)
• Spread: BYU (-7.5)
• Total: 48.5
• Time: 3:30 p.m. ET
• Date: Sept. 12
• TV Channel: FOX

Bet on BYU vs. Arizona with FanDuel Sportsbook.

Washington vs. Utah State

• Matchup: Utah State Aggies at No. 19 Washington Huskies
• Projected Favorite: Washington (94.80% win probability)
• Spread: Washington (-27.5)
• Total: 55.5
• Time: 3:30 p.m. ET
• Date: Sept. 12
• TV Channel: BTN

Bet on Washington vs. Utah State with FanDuel Sportsbook.

SMU vs. UC Davis

• Matchup: UC Davis Aggies at No. 17 SMU Mustangs
• Projected Favorite: SMU
• Spread: SMU (-26.5)
• Total: 58.5
• Time: 4 p.m. ET
• Date: Sept. 12
• TV Channel: ACC Network Extra

Bet on SMU vs. UC Davis with FanDuel Sportsbook.

Georgia Tech vs. Tennessee

• Matchup: No. 18 Tennessee Volunteers at Georgia Tech Yellow Jackets
• Projected Favorite: Tennessee (67.67% win probability)
• Spread: Tennessee (-11.5)
• Total: 55.5
• Time: 7 p.m. ET
• Date: Sept. 12
• TV Channel: ESPN

Bet on Georgia Tech vs. Tennessee with FanDuel Sportsbook.

Houston vs. Southern

• Matchup: Southern Jaguars at No. 22 Houston Cougars
• Projected Favorite: Houston
• Spread: Houston (-49.5)
• Total: 60.5
• Time: 7 p.m. ET
• Date: Sept. 12
• TV Channel: ESPN+

Bet on Houston vs. Southern with FanDuel Sportsbook.

Oregon State vs. Texas Tech

• Matchup: No. 13 Texas Tech Red Raiders at Oregon State Beavers
• Projected Favorite: Texas Tech (98.06% win probability)
• Spread: Texas Tech (-26.5)
• Total: 53.5
• Time: 7:30 p.m. ET
• Date: Sept. 12
• TV Channel: CBS/Paramount+

Bet on Oregon State vs. Texas Tech with FanDuel Sportsbook.

Texas vs. Ohio State

• Matchup: No. 1 Ohio State Buckeyes at No. 4 Texas Longhorns
• Projected Favorite: Ohio State (63.66% win probability)
• Spread: Texas (-1.5)
• Total: 49.5
• Time: 7:30 p.m. ET
• Date: Sept. 12
• TV Channel: ABC

Bet on Texas vs. Ohio State with FanDuel Sportsbook.

LSU vs. Louisiana Tech

• Matchup: Louisiana Tech Bulldogs at No. 8 LSU Tigers
• Projected Favorite: LSU (90.26% win probability)
• Spread: LSU (-35.5)
• Total: 55.5
• Time: 7:30 p.m. ET
• Date: Sept. 12
• TV Channel: SEC Network+

Bet on LSU vs. Louisiana Tech with FanDuel Sportsbook.

Iowa vs. Iowa State

• Matchup: Iowa State Cyclones at No. 21 Iowa Hawkeyes
• Projected Favorite: Iowa (77.03% win probability)
• Spread: Iowa (-13.5)
• Total: 40.5
• Time: 7:30 p.m. ET
• Date: Sept. 12
• TV Channel: NBC/Peacock

Bet on Iowa vs. Iowa State with FanDuel Sportsbook.

Ole Miss vs. Charlotte

• Matchup: Charlotte 49ers at No. 9 Ole Miss Rebels
• Projected Favorite: Ole Miss (99.48% win probability)
• Spread: Ole Miss (-46.5)
• Total: 60.5
• Time: 7:45 p.m. ET
• Date: Sept. 12
• TV Channel: ESPN2

Bet on Ole Miss vs. Charlotte with FanDuel Sportsbook.

Utah vs. Arkansas

• Matchup: Arkansas Razorbacks at No. 20 Utah Utes
• Projected Favorite: Utah (89.68% win probability)
• Spread: Utah (-12.5)
• Total: 55.5
• Time: 10:15 p.m. ET
• Date: Sept. 12
• TV Channel: ESPN

Bet on Utah vs. Arkansas with FanDuel Sportsbook.

USC vs. Louisiana

• Matchup: Louisiana Ragin' Cajuns at No. 14 USC Trojans
• Projected Favorite: USC (98.31% win probability)
• Spread: USC (-31.5)
• Total: 59.5
• Time: 11 p.m. ET
• Date: Sept. 12
• TV Channel: BTN

Bet on USC vs. Louisiana with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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