Astros vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for July 9

Odds updated as of 6:11 a.m.

Wednesday's slate in the MLB includes a matchup between the Houston Astros and the Cleveland Guardians.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Guardians Game Info

• Houston Astros (55-37) vs. Cleveland Guardians (42-48)
• Date: Wednesday, July 9, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CLEG

Astros vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-144) | CLE: (+122)
• Spread: HOU: -1.5 (+146) | CLE: +1.5 (-176)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Astros vs Guardians Probable Starting Pitchers

Probable Pitchers: Brandon Walter (Astros) - 1-1, 4.15 ERA vs Slade Cecconi (Guardians) - 3-4, 3.56 ERA

The probable pitchers are Brandon Walter (1-1) for the Astros and Slade Cecconi (3-4) for the Guardians. Walter and his team are 3-3-0 ATS this season when he starts. Walter's team has won 66.7% of his starts when they are favored on the moneyline (2-1). When Cecconi starts, the Guardians have gone 6-3-0 against the spread. The Guardians are 2-3 in Cecconi's five starts this season that they were the underdog on the moneyline.

Astros vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (67.8%)

Astros vs Guardians Moneyline

• Looking at the moneyline for Guardians-Astros, Cleveland is the underdog at +122, and Houston is -144 playing at home.

Astros vs Guardians Spread

• The Astros are 1.5-run home favorites on the runline against the Guardians. The Astros are +146 to cover, and the Guardians are -176.

Astros vs Guardians Over/Under

• A total of 7.5 runs has been set for the Astros-Guardians contest on July 9, with the over available at -115 and the under at -105.

Bet on Houston Astros vs. Cleveland Guardians on FanDuel today!

Astros vs Guardians Betting Trends

• The Astros have been victorious in 37, or 58.7%, of the 63 contests they have been chosen as favorites in this season.
• This season Houston has been victorious 16 times in 24 chances when named as a favorite of at least -144 on the moneyline.
• The Astros and their opponents have gone over the total this season in 38 of their 91 opportunities.
• The Astros are 47-44-0 against the spread in their 91 games that had a posted line this season.
• The Guardians have been the underdog on the moneyline 58 total times this season. They've finished 23-35 in those games.
• Cleveland is 8-13 (winning just 38.1% of its games) when playing as a moneyline underdog of +122 or longer.
• The Guardians have combined with opponents to go over the total 38 times this season for a 38-47-3 record against the over/under.
• The Guardians have covered 50% of their games this season, going 44-44-0 ATS.

Astros Player Leaders

• Isaac Paredes has 12 doubles, a triple, 19 home runs and 47 walks while hitting .255. He has an on-base percentage of .358 and a slugging percentage of .471.
• Among qualified hitters, he ranks 86th in batting average, his on-base percentage ranks 32nd, and he is 40th in slugging.
• Jose Altuve has 13 doubles, a triple, 16 home runs and 32 walks. He's batting .272 and slugging .456 with an on-base percentage of .332.
• He ranks 49th in batting average, 72nd in on-base percentage and 54th in slugging in the majors.
• Jake Meyers is batting .308 with a .405 slugging percentage and 21 RBI this year.
• Yainer Diaz has been key for Houston with 75 hits, an OBP of .275 plus a slugging percentage of .400.

Guardians Player Leaders

• Jose Ramirez has an on-base percentage of .364 and has 98 hits, both team-high numbers for the Guardians. He's batting .299 and slugging .503.
• Including all the qualifying hitters in the big leagues, his batting average ranks ninth, his on-base percentage is 27th, and he is 19th in slugging.
• Steven Kwan leads his team with a .409 slugging percentage. He has a batting average of .292 with an on-base percentage of .351.
• Including all qualifying hitters, he ranks 17th in batting average, 44th in on-base percentage and 92nd in slugging percentage.
• Carlos Santana has seven doubles, 10 home runs and 41 walks while batting .230.
• Angel Martinez has 13 doubles, a triple, six home runs and nine walks while hitting .238.

Astros vs Guardians Head to Head

• 7/8/2025: 10-6 CLE (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 7/7/2025: 7-5 CLE (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/8/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/7/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/6/2025: 4-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/28/2024: 4-3 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/27/2024: 5-2 HOU (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)

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