Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for June 16

Odds updated as of 10:13 a.m.

The Houston Astros will face the Athletics in MLB action on Monday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information about this game.

Astros vs Athletics Game Info

• Houston Astros (41-30) vs. Athletics (29-44)
• Date: Monday, June 16, 2025
• Time: 10:05 p.m. ET
• Venue: Sutter Health Park -- West Sacramento, California
• Coverage: NBCS-CA and SCHN

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-156) | OAK: (+132)
• Spread: HOU: -1.5 (-100) | OAK: +1.5 (-120)
• Total: 10.5 -- Over: (-100) | Under: (-122)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Lance McCullers (Astros) - 1-2, 4.91 ERA vs Mitch Spence (Athletics) - 2-1, 3.67 ERA

The Astros will give the nod to Lance McCullers (1-2, 4.91 ERA), who is eyeing win No. 2 on the season, and the Athletics will turn to Mitch Spence (2-1, 3.67 ERA). McCullers and his team have a record of 4-3-0 against the spread when he starts. When McCullers starts a game and his team is the favorite on the moneyline, they have a record of 1-3. Spence has started two games with set spreads, and the Athletics covered in both opportunities. The Athletics were the moneyline underdog for two Spence starts this season -- they split the games.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (50.1%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -156 favorite, while the Athletics are a +132 underdog at home.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are -100 to cover, while the Athletics are -120 to cover.

Astros vs Athletics Over/Under

• A combined run total of 10.5 has been set for Astros-Athletics on June 16, with the over at -100 and the under at -122.

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Astros vs Athletics Betting Trends

• The Astros have won in 27, or 57.4%, of the 47 contests they have been named as odds-on favorites in this year.
• This season, the Astros have come away with a win eight times in 14 chances when named as a favorite of at least -156 or better on the moneyline.
• The Astros and their opponents have hit the over in 27 of their 70 games with a total this season.
• In 70 games with a line this season, the Astros have a mark of 38-32-0 against the spread.
• The Athletics have won 34% of the games this season they were the underdog on the moneyline (18-35).
• In games they have played as a moneyline underdog with odds of +132 or longer, the Athletics have gone 6-18 (25%).
• The Athletics have combined with their opponents to go over the total 41 times this season for a 41-29-3 record against the over/under.
• The Athletics have a 35-38-0 record ATS this season.

Astros Player Leaders

• Jeremy Pena has 89 hits and an OBP of .379 to go with a slugging percentage of .485. All three of those stats are best among Houston hitters this season. He has a .325 batting average, as well.
• Among all qualified hitters in baseball, his batting average ranks fourth, his on-base percentage ranks 17th, and he is 30th in slugging.
• Isaac Paredes is hitting .255 with nine doubles, a triple, 15 home runs and 36 walks. He's slugging .478 with an on-base percentage of .353.
• Among qualifiers, he is 82nd in batting average, 46th in on-base percentage and 32nd in slugging percentage.
• Paredes has picked up a hit in two games in a row. In his last five games he is hitting .263 with two doubles, a home run, two walks and five RBIs.
• Jose Altuve has collected 73 base hits, an OBP of .322 and a slugging percentage of .425 this season.
• Jake Meyers has three home runs, 16 RBI and a batting average of .295 this season.
• Meyers has hit safely in three games in a row. During his last five outings he is hitting .235 with a double and three walks.

Athletics Player Leaders

• Jacob Wilson has racked up an on-base percentage of .401, a slugging percentage of .513, and has 98 hits, all club-bests for the Athletics (while batting .367).
• Including all the qualified hitters in the majors, he is second in batting average, sixth in on-base percentage and 14th in slugging percentage.
• Wilson hopes to build on a three-game hitting streak in this matchup. During his last five outings he is hitting .333 with a double and an RBI.
• Brent Rooker is hitting .278 with 16 doubles, a triple, 15 home runs and 30 walks. He's slugging .497 with an on-base percentage of .350.
• He is currently 39th in batting average, 51st in on-base percentage and 23rd in slugging percentage among all qualified hitters.
• Tyler Soderstrom has 11 doubles, a triple, 14 home runs and 33 walks while hitting .254.
• Lawrence Butler is batting .262 with 23 doubles, a triple, 10 home runs and 27 walks.

Astros vs Athletics Head to Head

• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 4-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/24/2024: 8-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 7/23/2024: 8-2 OAK (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/22/2024: 4-0 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/26/2024: 5-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 5/25/2024: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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