Yankees vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 1:11 a.m.

Thursday's slate in the MLB includes a matchup between the New York Yankees and the Boston Red Sox.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Yankees vs Red Sox Game Info

• New York Yankees (15-9) vs. Boston Red Sox (9-15)
• Date: Thursday, April 23, 2026
• Time: 6:10 p.m. ET
• Venue: Fenway Park -- Boston, Massachusetts
• Coverage: FS1, NESN+, and YES

Yankees vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-156) | BOS: (+132)
• Spread: NYY: -1.5 (+105) | BOS: +1.5 (-126)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Yankees vs Red Sox Probable Starting Pitchers

Probable Pitchers: Cam Schlittler (Yankees) - 2-1, 1.95 ERA vs TBA (Red Sox)

The Yankees will give the ball to Cam Schlittler (2-1), while the Red Sox's starter has not yet been announced. Schlittler and his team have a record of 4-1-0 against the spread when he starts. Schlittler's team is 3-1 this season when he starts and they are the moneyline favorite.

Yankees vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (61%)

Yankees vs Red Sox Moneyline

• Looking at the moneyline for Red Sox-Yankees, Boston is the underdog at +132, and New York is -156 playing on the road.

Yankees vs Red Sox Spread

• The Yankees are at the Red Sox and are favored by 1.5 runs (+105 to cover) on the runline. Boston is -126 to cover.

Yankees vs Red Sox Over/Under

• A combined run total of 8.5 has been set for Yankees-Red Sox on April 23, with the over at -105 and the under at -115.

Bet on New York Yankees vs. Boston Red Sox on FanDuel today!

Yankees vs Red Sox Betting Trends

• The Yankees have been victorious in 12, or 60%, of the 20 contests they have been chosen as favorites in this season.
• New York has a record of 6-5 in contests when bookmakers favor them by -156 or more on the moneyline.
• The Yankees and their opponents have hit the over in eight of their 22 games with a total set by oddsmakers this season.
• The Yankees are 12-10-0 against the spread in their 22 games with a line set by sportsbooks this season.
• The Red Sox have been the moneyline underdog a total of four times this season, and they've lost each of those games.
• Boston has never played a game this season with moneyline odds of +132 or longer.
• The Red Sox have played in 24 games with an over/under set, and have combined with opponents to go over the total 12 times (12-12-0).
• The Red Sox have collected a 7-17-0 record ATS this season (covering only 29.2% of the time).

Yankees Player Leaders

• Ben Rice leads New York in OBP (.456), slugging percentage (.743) and total hits (22) this season. He has a .314 batting average.
• Among all qualified batters, he ranks 13th in batting average, his on-base percentage ranks second, and he is second in slugging.
• Aaron Judge has three doubles, nine home runs and 15 walks. He's batting .241 and slugging .586 with an on-base percentage of .359.
• He ranks 96th in batting average, 49th in on-base percentage and eighth in slugging among qualifying hitters.
• Judge takes a three-game streak with at least one hit into this contest. During his last five outings he is hitting .267 with a double, a home run, seven walks and two RBIs.
• Cody Bellinger has hit three homers with a team-high .434 SLG this season.
• Trent Grisham has been key for New York with 11 hits, an OBP of .313 plus a slugging percentage of .338.

Red Sox Player Leaders

• Wilyer Abreu has put up a slugging percentage of .449 and has 25 hits, both team-best figures for the Red Sox. He's batting .281 and with an on-base percentage of .333.
• Including all qualifying hitters, he ranks 37th in batting average, while his on-base percentage ranks 82nd and he is 53rd in slugging.
• Willson Contreras paces his team with a .392 OBP. He has a batting average of .263 while slugging .438.
• He is 65th in batting average, 18th in on-base percentage and 64th in slugging percentage in MLB.
• Roman Anthony is batting .225 with three doubles, a triple, a home run and 16 walks.
• Jarren Duran has five doubles, a home run and six walks while hitting .194.

Yankees vs Red Sox Head to Head

• 4/22/2026: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/21/2026: 4-0 NYY (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 10/2/2025: 4-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 10/1/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/30/2025: 3-1 BOS (Favorite: Yankees, Spread: -1.5, Total: 6.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 9/14/2025: 6-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/13/2025: 5-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 9/12/2025: 4-1 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/24/2025: 7-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/23/2025: 12-1 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!