Diamondbacks vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 11:11 p.m.

On Thursday in MLB, the Arizona Diamondbacks are up against the Chicago White Sox.

We've got you covered, in terms of the most important info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Diamondbacks vs White Sox Game Info

• Arizona Diamondbacks (13-10) vs. Chicago White Sox (9-14)
• Date: Thursday, April 23, 2026
• Time: 3:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and CHSN

Diamondbacks vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-152) | CHW: (+128)
• Spread: ARI: -1.5 (+138) | CHW: +1.5 (-166)
• Total: 8.5 -- Over: (-120) | Under: (-102)

Diamondbacks vs White Sox Probable Starting Pitchers

Probable Pitchers: Mike Soroka (Diamondbacks) - 4-0, 2.78 ERA vs Davis Martin (White Sox) - 3-1, 2.16 ERA

The Diamondbacks will give the nod to Mike Soroka (4-0, 2.78 ERA), who is eyeing win No. 5 on the season, and the White Sox will turn to Davis Martin (3-1, 2.16 ERA). Soroka and his team have covered in each of the four games he's started with a spread this season. Soroka and his team have won each of the three games he's started as the moneyline favorite. The White Sox have a 3-1-0 ATS record in Martin's four starts that had a set spread. The White Sox have a 3-1 record in Martin's four starts this season when they were the moneyline underdog.

Diamondbacks vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (68.2%)

Diamondbacks vs White Sox Moneyline

• The Diamondbacks vs White Sox moneyline has Arizona as a -152 favorite, while Chicago is a +128 underdog on the road.

Diamondbacks vs White Sox Spread

• The Diamondbacks are hosting the White Sox and are favored by 1.5 runs on the spread. The Diamondbacks are +138 to cover the runline, with the White Sox being -166.

Diamondbacks vs White Sox Over/Under

• A combined run total of 8.5 has been set for Diamondbacks-White Sox on April 23, with the over at -120 and the under at -102.

Bet on Arizona Diamondbacks vs. Chicago White Sox on FanDuel today!

Diamondbacks vs White Sox Betting Trends

• The Diamondbacks have been chosen as favorites in six games this year and have walked away with the win five times (83.3%) in those games.
• Arizona has played as a favorite of -152 or more just one time this year and came away with a win in that game.
• The Diamondbacks and their opponents have gone over the total this season in 14 of their 23 opportunities.
• In 23 games with a line this season, the Diamondbacks have a mark of 17-6-0 against the spread.
• The White Sox have won 36.4% of the games this season they were the underdog on the moneyline (8-14).
• Chicago is 5-7 (winning 41.7% of its games) when it has played as a moneyline underdog of +128 or longer.
• In the 22 games oddsmakers have set an over/under for the White Sox, they have combined with opponents to go over the total 14 times (14-8-0).
• The White Sox have gone 10-12-0 against the spread this season.

Diamondbacks Player Leaders

• Corbin Carroll has 21 hits and an OBP of .391, both of which lead Arizona hitters this season. He has a .288 batting average and a slugging percentage of .575.
• Among qualifying hitters in the majors, he is 33rd in batting average, 19th in on-base percentage, and 12th in slugging.
• Ildemaro Vargas leads Arizona in slugging percentage (.623) thanks to nine extra-base hits. He's batting .361 with an on-base percentage of .381.
• Vargas takes a 16-game streak with at least one hit into this one. During his last 10 outings he is hitting .293 with four doubles, two home runs, a walk and seven RBIs.
• Geraldo Perdomo has collected 17 base hits, an OBP of .341 and a slugging percentage of .342 this season.
• Perdomo enters this matchup with five games in a row with at least one hit. In his last five games he is batting .474 with a double, a triple, two walks and an RBI.
• Ketel Marte has been key for Arizona with 19 hits, an OBP of .284 plus a slugging percentage of .379.
• Marte takes a two-game hitting streak into this game. During his last five outings he is hitting .238 with two walks.

White Sox Player Leaders

• Munetaka Murakami has an on-base percentage of .394 and has 18 hits, both team-best numbers for the White Sox. He's batting .234 and slugging .584.
• Including all qualified players, he ranks 106th in batting average, while his on-base percentage ranks 17th and he is 10th in slugging.
• Murakami enters this game on a four-game hitting streak. In his last five games he is hitting .381 with four home runs, four walks and eight RBIs.
• Miguel Vargas is hitting .177 with three doubles, a triple, four home runs and 15 walks. He's slugging .392 with an on-base percentage of .320.
• He is currently 170th in batting average, 110th in on-base percentage and 91st in slugging percentage among all qualified batters.
• Colson Montgomery is batting .213 with five doubles, six home runs and nine walks.
• Chase Meidroth leads his team with a .354 slugging percentage.

Diamondbacks vs White Sox Head to Head

• 4/21/2026: 11-5 CHW (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/25/2025: 7-3 CHW (Favorite: Diamondbacks, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/24/2025: 4-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/23/2025: 10-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/16/2024: 12-5 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
• 6/15/2024: 9-2 CHW (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/14/2024: 7-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 9/28/2023: 3-1 CHW (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/27/2023: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/26/2023: 15-4 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!