Yankees vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for May 7

Odds updated as of 2:11 p.m.

On Wednesday in MLB, the New York Yankees are up against the San Diego Padres.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Yankees vs Padres Game Info

• New York Yankees (20-16) vs. San Diego Padres (23-12)
• Date: Wednesday, May 7, 2025
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: MLB Network, Amazon Prime Video, and SDPA

Yankees vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-184) | SD: (+154)
• Spread: NYY: -1.5 (+114) | SD: +1.5 (-137)
• Total: 8 -- Over: (-106) | Under: (-114)

Yankees vs Padres Probable Starting Pitchers

Probable Pitchers: Max Fried (Yankees) - 6-0, 1.01 ERA vs Dylan Cease (Padres) - 1-2, 5.61 ERA

This contest's pitching matchup is set, as the Yankees will send Max Fried (6-0) to the mound, while Dylan Cease (1-2) will take the ball for the Padres. Fried's team is 6-1-0 against the spread this season in his starts. Fried has started seven games with his team as the moneyline favorite and won each of them. The Padres have a 3-4-0 record against the spread in Cease's starts. The Padres were the underdog on the moneyline for one Cease start this season -- they won.

Yankees vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (50%)

Yankees vs Padres Moneyline

• New York is a -184 favorite on the moneyline, while San Diego is a +154 underdog on the road.

Yankees vs Padres Spread

• The Yankees are favored by 1.5 runs at home versus the Padres. The Yankees are +114 to cover the spread, while the Padres are -137.

Yankees vs Padres Over/Under

• The over/under for the Yankees versus Padres game on May 7 has been set at 8, with -106 odds on the over and -114 odds on the under.

Bet on New York Yankees vs. San Diego Padres on FanDuel today!

Yankees vs Padres Betting Trends

• The Yankees have been chosen as favorites in 29 games this year and have walked away with the win 18 times (62.1%) in those games.
• New York has a record of 3-1 in contests when sportsbooks favor them by -184 or more on the moneyline.
• Contests with the Yankees have gone over the total set by oddsmakers in 16 of 35 chances this season.
• The Yankees have an against the spread mark of 17-18-0 in 35 games with a line this season.
• The Padres have won eight of the 16 games they were the underdog on the moneyline this season (50%).
• San Diego has not played a game this season with moneyline odds of +154 or longer.
• The Padres have combined with opponents to go over the total 14 times this season for a 14-19-1 record against the over/under.
• The Padres have put together a 20-14-0 record ATS this season (covering 58.8% of the time).

Yankees Player Leaders

• Aaron Judge leads New York with 56 hits and an OBP of .503, plus a team-best slugging percentage of .772. He's batting .412.
• Among all qualifying hitters in MLB, he ranks first in batting average, first in on-base percentage, and first in slugging.
• Paul Goldschmidt is hitting .351 with eight doubles, three home runs and 11 walks, while slugging .478 with an on-base percentage of .401.
• His batting average ranks second among qualified players, his on-base percentage eighth, and his slugging percentage 36th.
• Ben Rice has collected 29 base hits, an OBP of .362 and a slugging percentage of .573 this season.
• Rice brings a two-game hitting streak into this matchup. During his last five outings he is batting .250 with four doubles, a walk and two RBIs.
• Trent Grisham is batting .284 with a .370 OBP and 18 RBI for New York this season.

Padres Player Leaders

• Fernando Tatis Jr. has racked up an on-base percentage of .388, a slugging percentage of .557, and has 42 hits, all club-highs for the Padres (while batting .321).
• Including all qualifying hitters, he ranks seventh in batting average, while his on-base percentage is 18th and he is 12th in slugging.
• Manny Machado has 12 doubles, three home runs and 13 walks while hitting .300. He's slugging .462 with an on-base percentage of .361.
• Including all qualifying players, he is 21st in batting average, 46th in on-base percentage and 46th in slugging percentage.
• Luis Arraez is batting .289 with four doubles, a triple, three home runs and seven walks.
• Xander Bogaerts has nine doubles, a home run and 16 walks while hitting .246.

Yankees vs Padres Head to Head

• 5/6/2025: 12-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/5/2025: 4-3 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/26/2024: 5-2 SD (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/25/2024: 4-1 NYY (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 5/24/2024: 8-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 7, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/28/2023: 10-7 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/27/2023: 3-2 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 5/26/2023: 5-1 SD (Favorite: Padres, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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