Yankees vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 5

Odds updated as of 2:11 a.m.

The MLB schedule on Wednesday includes the New York Yankees facing the St. Louis Cardinals.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Yankees vs Cardinals Game Info

• New York Yankees (64-50) vs. St. Louis Cardinals (56-58)
• Date: Wednesday, August 5, 2026
• Time: 7:05 p.m. ET
• Venue: Yankee Stadium -- The Bronx, New York
• Coverage: Amazon Prime Video and Cardinals.TV

Yankees vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYY: (-152) | STL: (+128)
• Spread: NYY: -1.5 (+136) | STL: +1.5 (-164)
• Total: 8.5 -- Over: (-118) | Under: (-104)

Yankees vs Cardinals Probable Starting Pitchers

Probable Pitchers: Will Warren (Yankees) - 8-5, 4.14 ERA vs Andre Pallante (Cardinals) - 11-6, 3.72 ERA

The Yankees will give the ball to Will Warren (8-5, 4.14 ERA), who is eyeing win No. 9 on the season, and the Cardinals will turn to Andre Pallante (11-6, 3.72 ERA). Warren and his team are 11-10-0 ATS this season when he starts. Warren's team has been victorious in 73.3% of the games he's started as the moneyline favorite with a record of 11-4. The Cardinals have a 13-8-0 record against the spread in Pallante's starts. The Cardinals are 8-4 in Pallante's 12 starts this season that they were the moneyline underdog.

Yankees vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Yankees win (61.9%)

Yankees vs Cardinals Moneyline

• St. Louis is the underdog, +128 on the moneyline, while New York is a -152 favorite at home.

Yankees vs Cardinals Spread

• The Cardinals are at +1.5 on the runline against the Yankees. The Cardinals are -164 to cover the spread, and the Yankees are +136.

Yankees vs Cardinals Over/Under

• An over/under of 8.5 has been set for Yankees-Cardinals on Aug. 5, with the over being -118 and the under -104.

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Yankees vs Cardinals Betting Trends

• The Yankees have won in 53, or 59.6%, of the 89 contests they have been named as odds-on favorites in this year.
• This season New York has been victorious 27 times in 41 chances when named as a favorite of at least -152 on the moneyline.
• The Yankees and their opponents have hit the over in 48 of their 111 games with a total set by oddsmakers this season.
• The Yankees have an against the spread mark of 53-58-0 in 111 games with a line this season.
• The Cardinals have won 36 of the 77 games they were the underdog on the moneyline this season (46.8%).
• St. Louis has an 8-9 record (winning 47.1% of its games) when it has played as a moneyline underdog of +128 or longer.
• The Cardinals have had an over/under set by oddsmakers 111 times, and have combined with opponents to go over the total in 43 of those games (43-62-6).
• The Cardinals have a 59-52-0 record ATS this season (covering 53.2% of the time).

Yankees Player Leaders

• Ben Rice leads New York with an OBP of .353, plus a team-best slugging percentage of .553. He's batting .262 on the season.
• Among qualified batters in MLB, he ranks 62nd in batting average, 40th in on-base percentage, and third in slugging.
• Luis Garcia leads New York in total hits (104) this season while batting .285 with 49 extra-base hits. He's slugging .564 with an on-base percentage of .314.
• He ranks 20th in batting average, 108th in on-base percentage and second in slugging in the major leagues.
• Garcia has picked up a hit in three games in a row. In his last five games he is batting .350 with two doubles, a triple, two home runs and four RBIs.
• Trent Grisham has collected 69 base hits, an OBP of .314 and a slugging percentage of .385 this season.
• Grisham has logged a hit or more in two games in a row. During his last five outings he is hitting .176 with a double, a home run, a walk and an RBI.
• Jazz Chisholm is batting .218 with a .293 OBP and 46 RBI for New York this season.

Cardinals Player Leaders

• Alec Burleson has racked up a team-best .480 slugging percentage. He's batting .288 with an on-base percentage of .351.
• Including all qualifying hitters in the majors, he ranks 14th in batting average, 44th in on-base percentage and 30th in slugging percentage.
• Jordan Walker's 123 hits lead his team. He has a batting average of .285 while slugging .491 with an on-base percentage of .343.
• Including all qualifying hitters, his batting average places him 20th, his on-base percentage ranks 55th, and he is 21st in slugging.
• JJ Wetherholt is hitting .248 with 10 doubles, 16 home runs and 52 walks.
• Ivan Herrera has a .357 on-base percentage to lead his team.

Yankees vs Cardinals Head to Head

• 8/4/2026: 2-0 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -205, Underdog Moneyline: +186)
• 8/3/2026: 13-7 STL (Favorite: Yankees, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +215)
• 8/17/2025: 8-4 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/16/2025: 12-8 NYY (Favorite: Yankees, Spread: -1.5, Total: 7.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/15/2025: 4-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 9, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 9/1/2024: 14-7 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 8/31/2024: 6-5 STL (Favorite: Yankees, Spread: -1.5, Total: 9.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 8/30/2024: 6-3 NYY (Favorite: Yankees, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 7/2/2023: 5-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/1/2023: 6-2 NYY (Favorite: Cardinals, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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