White Sox vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 6

Odds updated as of 5:12 p.m.

The Chicago White Sox are among the MLB squads playing on Sunday, up against the Minnesota Twins.

We've got you covered, in terms of the most important information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

White Sox vs Twins Game Info

• Chicago White Sox (74-68) vs. Minnesota Twins (68-74)
• Date: Sunday, September 6, 2026
• Time: 6:20 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: NBCSN and Peacock

White Sox vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHW: (-146) | MIN: (+124)
• Spread: CHW: -1.5 (+142) | MIN: +1.5 (-172)
• Total: 8.5 -- Over: (-115) | Under: (-105)

White Sox vs Twins Probable Starting Pitchers

Probable Pitchers: Bryan Hudson (White Sox) - 4-4, 3.03 ERA vs Bailey Ober (Twins) - 7-4, 4.37 ERA

The probable pitchers are Bryan Hudson (4-4) for the White Sox and Bailey Ober (7-4) for the Twins. Hudson's team is 5-2-0 against the spread in his starts this season. Hudson's team is 2-1 this season when he starts and they are the moneyline favorite. The Twins have gone 12-8-0 ATS in Ober's 20 starts with a set spread. The Twins have an 8-5 record in Ober's 13 starts this season when they were the underdog on the moneyline.

White Sox vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: White Sox win (61.3%)

White Sox vs Twins Moneyline

• Minnesota is a +124 underdog on the moneyline, while Chicago is a -146 favorite at home.

White Sox vs Twins Spread

• The Twins are at the White Sox, and are +1.5 on the runline. The Twins are +142 to cover the spread, and the White Sox are -172.

White Sox vs Twins Over/Under

• The White Sox-Twins game on Sept. 6 has been given an over/under of 8.5 runs. The over is set at -115 and the under at -105.

Bet on Chicago White Sox vs. Minnesota Twins on FanDuel today!

White Sox vs Twins Betting Trends

• The White Sox have been victorious in 18, or 58.1%, of the 31 contests they have been chosen as favorites in this season.
• This season Chicago has come away with a win three times in four chances when named as a favorite of at least -146 on the moneyline.
• The White Sox and their opponents have hit the over in 76 of their 139 games with a total set by oddsmakers this season.
• The White Sox are 80-59-0 against the spread in their 139 games with a line set by sportsbooks this season.
• The Twins have compiled a 37-46 record in games they were the underdog on the moneyline (winning 44.6% of those games).
• When playing as a moneyline underdog with odds of +124 or longer, Minnesota has a record of 15-19 (44.1%).
• The Twins have played in 139 games with an over/under set, and have combined with opponents to go over the total 78 times (78-58-3).
• The Twins have a 75-64-0 record against the spread this season (covering 54% of the time).

White Sox Player Leaders

• Miguel Vargas leads Chicago with 130 hits, batting .251 this season with 61 extra-base hits. He has an on-base percentage of .362 and a slugging percentage of .486.
• Among qualifying hitters in baseball, his batting average ranks 75th, his on-base percentage ranks 25th, and he is 21st in slugging.
• Vargas has recorded a base hit in three games in a row. In his last five games he is batting .300 with a home run, a walk and two RBIs.
• Chase Meidroth has an OPS of .739, fueled by an OBP of .343 and a team-best slugging percentage of .396 this season. He's batting .271.
• Among qualifying batters, his batting average places him 40th, his on-base percentage 48th, and his slugging percentage 94th.
• Sam Antonacci leads Chicago with an OBP of .364 this season while batting .263 with 42 walks and 70 runs scored.
• Tristan Peters has been key for Chicago with 108 hits, an OBP of .345 plus a slugging percentage of .468.
• Peters takes a two-game hitting streak into this matchup. During his last five outings he is hitting .333 with a double, a triple and a walk.

Twins Player Leaders

• Brooks Lee has 22 doubles, three triples, 22 home runs and 33 walks while hitting .248. He's slugging .432 with an on-base percentage of .296.
• Including all the qualifying hitters in MLB, his batting average is 82nd, his on-base percentage is 123rd, and he is 58th in slugging.
• Josh Bell leads his team with a .427 slugging percentage. He has a batting average of .259 with an on-base percentage of .323.
• Including all qualified players, his batting average places him 65th, his on-base percentage is 84th, and he is 64th in slugging.
• Kody Clemens is leading the Twins with 110 hits.
• Luke Keaschall paces his team with a .366 OBP.

White Sox vs Twins Head to Head

• 9/5/2026: 6-4 MIN (Favorite: White Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/4/2026: 4-1 CHW (Favorite: White Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/30/2026: 5-1 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -114, Underdog Moneyline: +104)
• 8/29/2026: 3-2 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -110, Underdog Moneyline: +100)
• 8/28/2026: 7-4 CHW (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -126, Underdog Moneyline: +116)
• 6/3/2026: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/2/2026: 6-4 MIN (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/1/2026: 9-6 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 5/28/2026: 6-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 5/27/2026: 15-2 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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