Vanderbilt vs Kentucky College Basketball Prediction, Odds, Picks, Best Bets for Jan. 27

The Kentucky Wildcats (14-6, 5-2 SEC) hope to extend a five-game win streak when they visit the Vanderbilt Commodores (17-3, 4-3 SEC) on January 27, 2026 at Memorial Gymnasium. The contest airs on ESPN.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Vanderbilt vs. Kentucky Game Info and Odds

• Game day: Tuesday, January 27, 2026
• Game time: 9 p.m. ET
• TV channel: ESPN
• Location: Nashville, Tennessee
• Arena: Memorial Gymnasium

Vanderbilt vs. Kentucky Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Vanderbilt win (74.8%)

Read these betting insights and trends before you wager on Tuesday's Vanderbilt-Kentucky spread (Vanderbilt -5.5) or total (154.5 points).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Vanderbilt vs. Kentucky: ATS Betting Stats and Trends

• Vanderbilt has compiled an 11-9-0 record against the spread this season.
• Kentucky has put together an 8-12-0 ATS record so far this year.
• Vanderbilt covers the spread when it is a 5.5-point favorite or more 60% of the time. That's more often than Kentucky covers as an underdog of 5.5 or more (33.3%).
• Against the spread, the Commodores have played worse at home, covering five times in 10 home games, and four times in seven road games.
• In 2025-26 against the spread, the Wildcats have a better winning percentage at home (.462, 6-7-0 record) than away (.250, 1-3-0).
• Vanderbilt has beaten the spread three times in seven conference games.
• Kentucky has won twice against the spread in SEC play this season.

Vanderbilt vs. Kentucky: Moneyline Betting Stats

• Vanderbilt has won in 13, or 92.9%, of the 14 contests it has been named as the moneyline favorite in this year.
• The Commodores have yet to lose in 10 games when named as moneyline favorite of -265 or better.
• Kentucky has won one of the four games it was the underdog on the moneyline this season (25%).
• The Wildcats have played as a moneyline underdog of +215 or longer in just one game this season, which they won.
• Vanderbilt has an implied victory probability of 72.6% according to the moneyline set for this matchup.

Vanderbilt vs. Kentucky Head-to-Head Comparison

• Vanderbilt's +322 scoring differential (outscoring opponents by 16.1 points per game) is a result of scoring 90.1 points per game (10th in college basketball) while allowing 74.0 per outing (198th in college basketball).
• Vanderbilt's leading scorer, Tyler, ranks 119th in the nation averaging 17.4 points per game.
• Kentucky's +244 scoring differential (outscoring opponents by 12.2 points per game) is a result of putting up 82.5 points per game (70th in college basketball) while allowing 70.3 per outing (95th in college basketball).
• Kentucky's leading scorer, Otega Oweh, ranks 212th in the nation, averaging 16.1 points per game.
• The Commodores grab 33.4 rebounds per game (128th in college basketball) while conceding 30.5 per outing to their opponents. They outrebound opponents by 2.9 boards per game.
• Devin paces the team with 6.7 rebounds per game (198th in college basketball action).
• The 35.0 rebounds per game the Wildcats accumulate rank 67th in the country, 5.6 more than the 29.4 their opponents record.
• Malachi Moreno paces the Wildcats with 6.4 rebounds per game (235th in college basketball).
• Vanderbilt puts up 111.0 points per 100 possessions (sixth in college basketball), while allowing 91.1 points per 100 possessions (116th in college basketball).
• The Wildcats score 105.1 points per 100 possessions (44th in college basketball), while allowing 89.6 points per 100 possessions (77th in college basketball).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!