UTSA vs South Florida Prediction, Odds, Picks, Best Bets for Week 6 2026

College football's Thursday schedule includes the UTSA Roadrunners taking on the South Florida Bulls.

Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.

UTSA vs South Florida Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: UTSA: (-250) | South Florida: (+202)
• Spread: UTSA: -6.5 (-110) | South Florida: +6.5 (-110)
• Total: 49.5 -- Over: (-115) | Under: (-105)

UTSA vs South Florida Betting Trends

• UTSA has covered the spread three times in five games.
• UTSA has won once ATS (1-2) as a 6.5-point or higher favorite this year.
• Two of five UTSA games have hit the over this year.
• South Florida has posted two wins against the spread this year.
• South Florida has played two games (out of five) which finished over the total this year.

UTSA vs South Florida Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Roadrunners win (54.4%)

UTSA vs South Florida Point Spread

UTSA is favored by 6.5 points against South Florida. UTSA is -110 to cover the spread, while South Florida is -110.

UTSA vs South Florida Over/Under

The over/under for the UTSA versus South Florida matchup on Oct. 8 has been set at 49.5, with -115 odds on the over and -105 odds on the under.

UTSA vs South Florida Moneyline

South Florida is a +202 underdog on the moneyline, while UTSA is a -250 favorite.

UTSA vs. South Florida Points Insights

UTSA vs. South Florida Game Info

• Game day: Thursday, October 8, 2026
• Game time: 7:30 p.m. ET
• TV channel: ESPN
• Location: San Antonio, Texas
• Stadium: Alamodome

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Check out even more in-depth UTSA vs. South Florida analysis on FanDuel Research.