USC vs Colorado Prediction, Odds, & Betting Trends for College Football Week 5 Game

Data Skrive

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The Saturday schedule in college football includes a matchup between the USC Trojans and the Colorado Buffaloes.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

USC vs Colorado Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: USC: (-1450) | Colorado: (+810)
Spread: USC: -21.5 (-114) | Colorado: +21.5 (-106)
Total: 72.5 -- Over: (-115) | Under: (-105)

USC has won twice against the spread this season.
USC has two wins ATS (2-2) as a 21.5-point or higher favorite in 2023.
Out of four USC games so far this season, three have gone over the total.
Colorado has won twice against the spread this season.
Colorado is winless ATS (0-1) when playing as at least 21.5-point underdogs this year.
Colorado has played two games (out of four) which finished over the total this year.

All college football win probability predictions and picks are according to numberFire.
Prediction: Trojans win (92.4%)

USC is favored by 21.5 points versus Colorado. USC is -114 to cover the spread, while Colorado is -106.

A total of 72.5 points has been set for the USC-Colorado game on September 30, with the over available at -115 and the under at -105.

Looking at the moneyline for Colorado-USC, Colorado is the underdog at +810, and USC is -1450.

	Point Scored (PG)	Points Scored CFB Rank	Points Allowed (PG)	Points Allowed CFB Rank	Average Total	Games Over Current Total	Total Games
USC	55	1	20	45	65.3	2	4
Colorado	32.5	58	33.3	107	63.5	2	4

Check out even more in-depth USC vs. Colorado analysis on FanDuel Research.

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