Twins vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 4

Odds updated as of 7:13 p.m.

The Minnesota Twins versus the Chicago White Sox is on the MLB schedule for Thursday.

All the information you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Twins vs White Sox Game Info

• Minnesota Twins (62-77) vs. Chicago White Sox (52-88)
• Date: Thursday, September 4, 2025
• Time: 7:40 p.m. ET
• Venue: Target Field -- Minneapolis, Minnesota
• Coverage: MNNT and CHSN

Twins vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIN: (-146) | CHW: (+124)
• Spread: MIN: -1.5 (+140) | CHW: +1.5 (-170)
• Total: 8.5 -- Over: (-118) | Under: (-104)

Twins vs White Sox Probable Starting Pitchers

Probable Pitchers: Taj Bradley (Twins) - 6-7, 4.82 ERA vs Fraser Ellard (White Sox) - 0-2, 4.82 ERA

This contest's pitching matchup is set, as the Twins will send Taj Bradley (6-7) to the mound, while Fraser Ellard (0-2) will take the ball for the White Sox. When Bradley starts, his team is 10-13-0 against the spread this season. Bradley's team is 5-5 this season when he starts and they are the moneyline favorite. Ellard has started only one game with a set spread, which the White Sox covered. The White Sox were named the moneyline underdog for one Ellard start this season -- they won.

Twins vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (62.1%)

Twins vs White Sox Moneyline

• Minnesota is a -146 favorite on the moneyline, while Chicago is a +124 underdog on the road.

Twins vs White Sox Spread

• The Twins are 1.5-run home favorites on the runline against the White Sox. The Twins are +140 to cover, and the White Sox are -170.

Twins vs White Sox Over/Under

• The Twins-White Sox game on Sept. 4 has been given an over/under of 8.5 runs. The over is set at -118 and the under at -104.

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Twins vs White Sox Betting Trends

• The Twins have won in 39, or 48.8%, of the 80 contests they have been named as odds-on favorites in this year.
• This year Minnesota has won 17 of 30 games when listed as at least -146 on the moneyline.
• The Twins and their opponents have hit the over in 63 of their 134 games with a total set by oddsmakers this season.
• In 134 games with a line this season, the Twins have a mark of 65-69-0 against the spread.
• The White Sox are 48-84 in games they were the underdog on the moneyline (winning 36.4% of those games).
• Chicago has gone 32-63 when it has played as a moneyline underdog with odds of +124 or longer (33.7%).
• The White Sox have combined with opponents to hit the over on the total 62 times this season for a 62-65-8 record against the over/under.
• The White Sox have collected a 76-59-0 record against the spread this season (covering 56.3% of the time).

Twins Player Leaders

• Byron Buxton leads Minnesota in slugging percentage (.559) and total hits (112) this season. He's batting .273 with an on-base percentage of .333.
• Among qualified batters in the majors, he ranks 38th in batting average, 70th in on-base percentage, and fifth in slugging.
• Buxton hopes to build on a seven-game hitting streak in this matchup. During his last 10 games he is hitting .282 with three doubles, two triples, four home runs, three walks and 10 RBIs.
• Trevor Larnach has hit 16 homers this season while driving in 55 runs. He's batting .254 this season and slugging .413 with an on-base percentage of .327.
• Among all qualified, he ranks 89th in batting average, 83rd in on-base percentage and 90th in slugging percentage.
• Larnach has picked up at least one hit in five straight games. During his last five outings he is batting .526 with a double, a walk and four RBIs.
• Brooks Lee has 101 hits this season and has a slash line of .242/.290/.379.
• Ryan Jeffers has 101 hits this season and a team-best OBP of .352.

White Sox Player Leaders

• Andrew Benintendi has 15 doubles, two triples, 17 home runs and 35 walks while hitting .244. He's slugging .425 with an on-base percentage of .306.
• Lenyn Sosa leads his team with 119 hits and has a club-high .434 slugging percentage. He has a batting average of .265 with an on-base percentage of .295.
• Including all qualified players, he is 60th in batting average, 137th in on-base percentage and 78th in slugging percentage.
• Chase Meidroth is batting .251 with 14 doubles, four home runs and 38 walks.
• Mike Tauchman is hitting .271 with 15 doubles, a triple, eight home runs and 40 walks.

Twins vs White Sox Head to Head

• 9/3/2025: 4-3 CHW (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 9/2/2025: 12-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/1/2025: 6-5 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/24/2025: 8-0 CHW (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/23/2025: 7-3 CHW (Favorite: Twins, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 8/22/2025: 9-7 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/24/2025: 3-0 CHW (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
• 4/23/2025: 6-3 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 4/22/2025: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 4/2/2025: 6-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)

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