Twins vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 7:11 a.m.
The MLB's Wednesday schedule includes the Minnesota Twins taking on the Chicago White Sox.
Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.
Twins vs White Sox Game Info
- Minnesota Twins (8-15) vs. Chicago White Sox (5-18)
- Date: Wednesday, April 23, 2025
- Time: 7:40 p.m. ET
- Venue: Target Field -- Minneapolis, Minnesota
- Coverage: MNNT and CHSN
Twins vs White Sox Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: MIN: (-275) | CHW: (+225)
- Spread: MIN: -1.5 (-138) | CHW: +1.5 (+115)
- Total: 8.5 -- Over: (-105) | Under: (-115)
Twins vs White Sox Probable Starting Pitchers
Probable Pitchers: David Festa (Twins) - 0-0, 0.00 ERA vs Bryse Wilson (White Sox) - 0-0, 4.50 ERA
This contest's pitching matchup is set, as the Twins will send David Festa to the mound, while Bryse Wilson will get the nod for the White Sox. Festa has a record of 1-1-0 ATS in two starts with a spread this season. Festa's team is 1-1 this season when he starts and they're favored on the moneyline. Last season Wilson and his team went 5-4-0 against the spread when he pitched. Wilson's team went 2-3 in games he appeared in when they were moneyline underdogs a season ago.
Twins vs White Sox Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Twins win (72.8%)
Twins vs White Sox Moneyline
- Minnesota is the favorite, -275 on the moneyline, while Chicago is a +225 underdog on the road.
Twins vs White Sox Spread
- The Twins are 1.5-run home favorites on the runline against the White Sox. The Twins are -138 to cover, and the White Sox are +115.
Twins vs White Sox Over/Under
- Twins versus White Sox on April 23 has an over/under of 8.5 runs, with the odds on the over -105 and the under set at -115.
Bet on Minnesota Twins vs. Chicago White Sox on FanDuel today!
Twins vs White Sox Betting Trends
- The Twins have been favorites in 16 games this season and have come away with the win seven times (43.8%) in those contests.
- Oddsmakers have given Minnesota the best odds of winning it has seen this season, with a -275 moneyline listed for this contest.
- Contests with the Twins have gone over the total set by bookmakers in eight of 23 chances this season.
- The Twins have posted a record of 10-13-0 against the spread this season.
- The White Sox have put together a 5-18 record in games they were the underdog on the moneyline (winning 21.7% of those games).
- When it has played as a moneyline underdog with odds of +225 or longer, Chicago has a record of 1-2 (33.3%).
- The White Sox have combined with opponents to hit the over on the total nine times this season for a 9-12-2 record against the over/under.
- The White Sox have put together an 11-12-0 record against the spread this season.
Twins Player Leaders
- Byron Keiron Buxton leads Minnesota with 19 hits and a team-best slugging percentage of .451. He's batting .232 with an on-base percentage of .264.
- Among qualifying hitters in the majors, his batting average ranks 103rd, his on-base percentage ranks 144th, and he is 59th in slugging.
- Ty France is slashing .238/.322/.350 this season and leads the Twins with an OPS of .672.
- Among qualified hitters, his batting average places him 92nd, his on-base percentage 93rd, and his slugging percentage 122nd.
- Trevor Larnach is batting .200 with a .293 slugging percentage and seven RBI this year.
- Larnach takes a four-game hitting streak into this matchup. During his last five outings he is hitting .235 with two home runs, two walks and three RBI.
- Carlos Javier Correa has one home run, five RBI and a batting average of .184 this season.
White Sox Player Leaders
- Andrew Sebastian Benintendi is batting .241 with four home runs and four walks. He's slugging .463 with an on-base percentage of .293.
- Luis Robert has two doubles, two home runs and 12 walks while batting .151. He's slugging .260 with an on-base percentage of .267.
- He ranks 172nd in batting average, 140th in on-base percentage and 166th in slugging percentage in the majors.
- Matt Thaiss is batting .222 with two doubles, a home run and 10 walks.
- Brooks Baldwin is batting .258 with two doubles, two home runs and two walks.
Twins vs White Sox Head to Head
- 4/22/2025: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
- 4/2/2025: 6-1 MIN (Favorite: Twins, Spread: -1.5, Total: 7, Favorite Moneyline: -188, Underdog Moneyline: +158)
- 4/1/2025: 8-3 MIN (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -164, Underdog Moneyline: +138)
- 3/31/2025: 9-0 CHW (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
- 8/4/2024: 13-7 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -310, Underdog Moneyline: +250)
- 8/3/2024: 6-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
- 8/2/2024: 10-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -320, Underdog Moneyline: +260)
- 7/10/2024: 3-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -220, Underdog Moneyline: +184)
- 7/10/2024: 3-1 CHW (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -162, Underdog Moneyline: +136)
- 7/8/2024: 8-6 MIN (Favorite: Twins, Spread: -1.5, Total: 9, Favorite Moneyline: -200, Underdog Moneyline: +168)
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